{
  "url": "https://openlegislation.uk/cosmetic-products-safety-regulations-2003/schedule-4/part-I",
  "json_url": "https://openlegislation.uk/cosmetic-products-safety-regulations-2003/schedule-4/part-I.json",
  "legislation": "uksi/2003/835",
  "legislation_title": "The Cosmetic Products (Safety) Regulations 2003",
  "legislation_url": "https://openlegislation.uk/cosmetic-products-safety-regulations-2003",
  "path": "schedule/4/part/I",
  "kind": "part",
  "number": "I",
  "heading": "SUBSTANCES LISTED IN ANNEX III, PART 1 OF THE DIRECTIVE AS SUBSTANCES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO THE RESTRICTIONS LAID DOWN",
  "text": "(1)\n(2)\n(3)\n(4)\n(5)\n(6)\nReference Number\nName of substance\nPurpose of substance or type of product\nMaximum concentration of substance in product\nOther requirements\nRequired information\nNote 1: These substances may be used singly or in combination provided that the sum of the ratios of the levels of each of them in the cosmetic product expressed with reference to the maximum level authorised for each of them does not exceed 1.\nNote 2: The concentration of sodium, potassium or lithium hydroxide is expressed as a percentage of sodium hydroxide. In cases of mixtures, the sum must not exceed the limits given in column (4).\n1a\nBoric acid, borates, and tetraborates\nTalcum powder\n5 per cent\nNot to be used in products intended for children under three years old\nNot to be used in products intended for peeling or irritated skin if the concentration of free soluble borate exceeds 1.5 per cent calculated as boric acid\nNot to be used for bathing children under three years old\nDo not use on peeling or irritated skin (Only required if the concentration of free soluble borate exceeds 1.5 per cent calculated as boric acid)\nOral hygiene products\n0.1 per cent\nNot to be used in products intended for children under three years old\nDo not swallow\nNot to be used for children under three years old\nOther products (excluding bath products and hair waving products)\n3 per cent\nNot to be used in products intended for children under three years old\nNot to be used in products intended for peeling or irritated skin if the concentration of free soluble borate exceeds 1.5 per cent calculated as boric acid\nNot to be used for children under three years old\nDo not use on peeling or irritated skin (Only required if the concentration of free soluble borate exceeds 1.5 per cent calculated as boric acid)\nThe above-mentioned percentages are calculated as boric acid\n1b\nTetraborates\nBath products\n18 per cent\nNot to be used in products for children under three years old\nNot to be used for bathing children under three years old\nHair waving products\n8 per cent\nThe above-mentioned percentages are calculated as boric acid\n2a\nThioglycolic acid and its salts\n(a) Hair waving or straightening products for general use\n8 per cent ready for use\npH 7 to 9.5\nContains thioglycolate. Follow the instructions. Keep out of reach of children\n(b) Hair waving or straightening products for professional use\n11 per cent ready for use\npH 7 to 9.5\nContains thioglycolate. Follow the instructions. Keep out of reach of children. For professional use only\n(c) Depilatories\n5 per cent ready for use\npH 7 to 12.7\nContains thioglycolate. Follow the instructions. Keep out of reach of children\n(d) Other hair-care products which are removed after application\n2 per cent ready for use\npH 7 to 9.5\nContains thioglycolate. Follow the instructions. Keep out of reach of children\nThe above-mentioned percentages are calculated as thioglycolic acid\n(a), (b), (c) and (d): The directions for use must incorporate the following:\n— Avoid contact with eyes\n— In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice\n— Wear suitable gloves ((a), (b) and (d) only)\n2b\nThioglycolic acid esters\n(a) Hair waving or straightening products for general use\n8 per cent ready for use\npH 6 to 9.5\nContains thioglycolate. Follow the instructions. Keep out of reach of children\n(b) Hair waving or straightening products for professional use\n11 per cent ready for use\npH 6 to 9.5\nContains thioglycolate. Follow the instructions. Keep out of reach of children. For professional use only\nThe above-mentioned percentages are calculated as thioglycolic acid\n(a) and (b): The directions for use must incorporate the following:\n— May cause sensitization in the event of skin contact\n— Avoid contact with eyes\n— In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice\n— Wear suitable gloves\n3\nOxalic acid, its esters and alkaline salts\nHair care products\n5 per cent\n—\nFor professional use only\n4\nAmmonia\nAll purposes and products\n6 per cent calculated as NH3\n—\nContains ammonia (not required when concentration is not more than 2 per cent)\n5\nTosylchlora-mide sodium (INN) [Chloramine-T]\nAll purposes and products\n0.2 per cent\n—\n—\n6\nChlorates of alkali metals\nToothpaste\n5 per cent\n—\n—\nOther uses\n3 per cent\n—\n—\n7\nDichloro-methane\nAll purposes and products\n35 per cent (and when mixed with 1,1,1-trichloroethane, total concentration must not exceed 35 per cent)\nPurity of the dichloromethane must be not less than 99.8 per cent\n—\n8\nm- and p-Phenylenedia-mines, their N-substituted derivatives and their salts;\nN-substituted derivatives of o-phenylenediamines (see Note 1), with the exception of those derivatives listed elsewhere in this Schedule\nOxidizing colouring agents for hair-dyeing for general use\n6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains phenylenediamines Can cause an allergic reaction. Do not use to dye eyelashes or eyebrows\nOxidizing colouring agents for hair-dyeing for professional use\n6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains phenylenediamines. For professional use only. Can cause an allergic reaction. Wear suitable gloves\n9\nMethylphenylenediamines (other than 4-methyl-m-phenylenediamine and its salts), their N-substituted derivatives and their salts (Toluenediamines (other than toluene-1, 3-diamine and its salts), their N-substituted derivatives and their salts)\nOxidizing colouring agents for hair-dyeing for general use\n10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains phenylene-diamines. Can cause an allergic reaction. Do not use to dye eyelashes or eyebrows\nOxidizing colouring agents for hair-dyeing for professional use\n10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains phenylenediamines. For professional use only. Can cause an allergic reaction. Wear suitable gloves\n10\nDiaminophenols\nOxidizing colouring agents for hair-dyeing for general use\n10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains diaminophenols. Can cause allergic reaction. Do not use to dye eyelashes or eyebrows\nOxidizing colouring agents for hair-dyeing for professional use\n10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below\n—\nContains diaminophenols. For professional use only. Can cause allergic reaction. Wear suitable gloves\n11\nDichlorophen (INN) [Dichlorophene]\nAll purposes and products\n0.5 per cent\n—\nContains dichlorophen\n12\nHydrogen peroxide and other compounds or mixtures that release hydrogen peroxide including hydrogen peroxide-urea (hydrogen peroxide-carbamide) and zinc peroxide\n(a) Hair-care preparations\n(b) Skin-care preparations\n(c) Nail hardening preparations\n(d) Oral hygiene products\n12 per cent of H2O2 present or released\n4 per cent of H2O2 present or released\n2 per cent of H2O2 present or released\n0.1 per cent of H2O2 present or released\n—\n—\n—\n(a): Wear suitable gloves\n(a)(b)(c): Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them\n—\n13\nFormaldehyde (see also Part I of Schedule 6)\nNail hardeners\n5 per cent\n—\nContains formaldehyde. Protect cuticles with grease or oil. (Not required when concentration is not more than 0.05 per cent)\n14\nHydroquinone\nOxidizing colouring agent for hair dyeing for general use\n0.3 per cent subject to the provisions of “Combination Rule B” set out below\n—\nContains hydroquinone. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them\nOxidizing colouring agent for hair dyeing for professional use\n0.3 per cent subject to the provisions of “Combination Rule B” set out below\n—\nContains hydroquinone. For professional use only. Rinse eyes immediately if product comes into contact with them\n15a\nPotassium hydroxide and sodium hydroxide\nNail cuticle solvent\n5 per cent calculated as sodium hydroxide (see Note 2)\n—\nContains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children\nHair straightener for general use\n2 per cent calculated as sodium hydroxide (see Note 2)\n—\nContains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children\nHair straightener for professional use\n4.5 per cent calculated as sodium hydroxide (see Note 2)\n—\nFor professional use only. Avoid contact with eyes. Can cause blindness\npH adjuster for depilatories\n—\npH value not to exceed 12.7\nKeep out of reach of children Avoid contact with eyes\nOther uses as pH adjuster\n—\npH value not to exceed 11\n—\n15b\nLithium hydroxide\nHair straightener for general use\n2 per cent calculated as sodium hydroxide (see Note 2)\n—\nContains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children\nHair straightener for professional use\n4.5 per cent calculated as sodium hydroxide (see Note 2)\n—\nFor professional use only. Avoid contact with eyes. Can cause blindness\npH adjuster for depilatories\n—\npH value not to exceed 12.7\nContains alkali. Keep out of reach of children. Avoid contact with eyes\nOther uses as pH adjuster (for rinse-off products only)\n—\npH value not to exceed 11\n—\n15c\nCalcium hydroxide\nHair straighteners containing two components: calcium hydroxide and aguanidine salt\n7 per cent by weight of calcium hydroxide\n—\nContains alkali. Avoid contact with eyes. Keep out of reach of children. Can cause blindness\npH adjuster for depilatories\n—\npH value not to exceed 12.7\nContains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children\nOther uses e.g. pH adjuster processing aid\n—\npH value not to exceed 11\n—\n16\nα-Naphthol [1-Naphthol] and its salts\nOxidising colouring agents for hair dyeing\n2 per cent\nIn combination with hydrogen peroxide the maximum use concentration upon application is 1 per cent\nCan cause allergic reaction\n17\nSodium nitrite\nRust inhibitor\n0.2 per cent\nDo not use with secondary and/or tertiary amines or other substances forming nitrosamines\n—\n18\nNitromethane\nRust inhibitor\n0.3 per cent\n—\n—\n19\nPhenol and its alkali salts\nSoaps and shampoos\n1 per cent calculated as phenol\n—\nContains phenol\n20\nENTRY DELETED\n21\nQuinine and its salts\nShampoos\n0.2 per cent calculated as quinine base\n—\n—\nHair lotions\n0.5 per cent calculated as quinine base\n—\n—\n22\nResorcinol\nOxidizing colouring agent for hair dyeing for general use\n5 per cent subject to the provisions of “Combination Rule B” set out below\n—\nContains resorcinol. Rinse hair well after application. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them\nOxidizing colouring agent for hair dyeing for professional use\n5 per cent subject to the provisions of “Combination Rule B” set out below\n—\nContains resorcinol. For professional use only. Rinse eyes immediately if product comes into contact with them\nHair lotions and shampoos\n0.5 per cent subject to the provisions of “Combination Rule B” set out below\n—\nContains resorcinol\n23a\nAlkali sulphides\nDepilatories\n2 per cent calculated as sulphur\npH value not to exceed 12.7\nKeep out of reach of children. Avoid contact with eyes\n23b\nAlkaline earth sulphides\nDepilatories\n6 per cent calculated as sulphur\npH value not to exceed 12.7\nKeep out of reach of children. Avoid contact with eyes\n24\nWater-soluble zinc salts with the exception of zinc 4-hydroxybenzene-sulphonate\nAll purposes and products\n1 per cent calculated as zinc\n—\n—\n25\nZinc 4-hydroxybenzene-sulphonate [Zinc phenolsulfonate]\nDeodorants, antiperspirants and astringent lotions\n6 per cent calculated as percentage of anhydrous substance\n—\nAvoid contact with eyes\n26\nAmmonium monofluoro-phosphate\nOral hygiene products\n0.15 per cent calculated as fluorine. When mixed with other fluorine compounds the total fluorine concentration must not exceed 0.15 per cent\n—\nContains ammonium monofluorophosphate\n27\nSodium monofluoro-phosphate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains sodium monofluoro-phosphate\n28\nPotassium monofluoro-phosphate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains potassium monofluoro-phosphate\n29\nCalcium monofluoro-phosphate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains calcium monofluoro-phosphate\n30\nCalcium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains calcium fluoride\n31\nSodium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains sodium fluoride\n32\nPotassium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains potassium fluoride\n33\nAmmonium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains ammonium fluoride\n34\nAluminium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains aluminium fluoride\n35\nStannous fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains stannous fluoride\n36\nHexadecylammonium fluoride [Cetylamine hydrofluoride]\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains hexadecylammonium fluoride\n37\n3-(n-Hexadecyl-N-2-hydroxyethylammonio)-propylbis(2-hydroxyethyl)-ammonium difluoride [Stearyl trihydroxyethyl propylenediamine dihydrofluoride]\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains 3-(n-hexadecyl-N-2-hydroxyethylammonio)- propylbis(2-hydroxyethyl)- ammoniumdifluoride\n38\nN,N',N'-Tris(polyoxyethylene)-N-hexadecylpropyl-enediamine dihydrofluoride [Palmityl trihydroxyethyl propylenediamine dihydrofluoride]\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains N,N',N'-tris (polyoxyethylene)-N-hexa-decylpropylenediamine dihydrofluoride\n39\nOctadecenylammonium fluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains octadecenylammonium fluoride\n40\nSodium fluorosilicate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains sodium fluorosilicate\n41\nPotassium fluorosilicate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains potassium fluorosilicate\n42\nAmmonium fluorosilicate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains ammonium fluorosilicate\n43\nMagnesium fluorosilicate\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains magnesium fluorosilicate\n44\n1,3-Bis(hydroxymethyl)-imidazolidene-2-thione [Dimethylol ethylene thiourea]\nHair care preparations\n2 per cent\nNot to be used in aerosol dispensers\nContains 1,3-bis(hydroxymethyl) imidazolidene-2-thione\nNail care preparations\n2 per cent\npH value as applied must be less than 4\nContains 1,3-bis(hydroxymethyl) imidazolidene-2-thione\n45\nBenzyl alcohol (See also Part I of Schedule 6)\nSolvent, perfumes and flavourings\n—\n—\n—\n46\n6-Methylcoumarin\nOral hygiene products\n0.003 per cent\n—\n—\n47\nNicomethanol hydrofluoride\nOral hygiene products\nAs for ammonium monofluorophosphate\n—\nContains nicomethanol hydrofluoride\n48\nSilver nitrate\nProducts to dye eyelashes or eyebrows\n4 per cent\n—\nContains silver nitrate. Rinse eyes immediately if product comes into contact with them\n49\nSelenium disulphide [Selenium sulfide]\nAnti-dandruff shampoos\n1 per cent\n—\nContains selenium disulphide. Avoid contact with eyes or damaged skin\n50\nAluminium zirconium chloride hydroxide complexes AlxZr(OH)yClz and aluminium zirconium chloride hydroxide glycine complexes\nAnti-perspirants\n20 per cent as anhydrous aluminium zirconium chloride hydroxide, 5.4 per cent as zirconium\nThe ratio of the number of aluminium atoms to that of zirconium atoms must be between 2 and 10\nThe ratio of the number of (Al + Zr) atoms to chlorine atoms must be between 0.9 and 2.1\nNot to be used in aerosol dispensers (sprays)\nDo not apply to irritated or damaged skin\n51\nQuinolin-8-ol and bis-(8-hydroxyquinolinium sulphate) (See also Part I of Schedule 3) [Oxyquinoline and Oxyquinoline sulfate]\nStabilizer for hydrogen peroxide in rinse-off hair care preparations\n0.3 per cent calculated as base\n—\n—\nStabilizer for hydrogen peroxide in non rinse-off hair care preparations\n0.03 per cent calculated as base\n—\n—\n52\nMethanol\nDenaturant for ethanol and isopropyl alcohol\n5 per cent calculated as a percentage of ethanol and isopropyl alcohol\n—\n—\n53\nEtidronic acid and its salts (1-hydroxyethylidene-diphosphonic acid and its salts)\nHair care\n1.5 per cent expressed as etidronic acid\n—\n—\nSoap\n0.2 per cent expressed as etidronic acid\n—\n—\n54\n1-Phenoxy-propan-2-ol (See also Part I of Schedule 6) [Phenoxy-isopropanol]\nProducts rinsed off after use\n2 per cent\nProhibited in oral hygiene products\n—\n55\nLead acetate\nOnly for hair dyeing\n0.6 per cent calculated as lead\n—\nContains lead acetate. Keep away from children. Avoid all contact with the eyes. Wash hands after use. Do not use to dye eyelashes, eyebrows or moustaches\nIf irritation develops discontinue use\n56\nMagnesium fluoride\nDental hygiene products\n0.15 per cent calculated as fluorine. When mixed with other fluorine compounds the total fluorine concentration must not exceed 0.15 per cent\n—\nContains magnesium fluoride\n57\nStrontium chloride hexahydrate\n(a) Toothpaste\n3.5 per cent calculated as strontium. When mixed with other permitted strontium compounds the total strontium content must not exceed 3.5 per cent\n—\nContains strontium chloride Frequent use by children is not advisable\n(b) Shampoo and face care products\n2.1 per cent calculated as strontium. When mixed with other permitted strontium compounds the total strontium content must not exceed 2.1 per cent\n—\n—\n58\nStrontium acetate hemihydrate\nToothpaste\n3.5 per cent calculated as strontium. When mixed with other permitted strontium products the total strontium content must not exceed 3.5 per cent\n—\nContains strontium acetate. Use by children is not advisable\n59\nTalc: hydrated magnesium silicate\n(a) Powdery products intended to be used for children under three years of age\n—\n—\na): Keep powder away from children’s nose and mouth\n(b) other products\n—\n—\n60\nFatty acid dialkanolamides\nAll purposes and products\nMaximum dialkanolamine content: 0.5 per cent\nDo not use with nitrosating systems. Maximum dialkanolamine content: 5 per cent (applies to raw materials. Maximum N-nitroso-dialkanolamine content: 50 μg/kg (applies to raw materials). Keep in nitrite-free containers\n—\n61\nMonoalkanolamines\nAll purposes and products\nMaximum dialkanolamine content: 0.5 per cent\nDo not use with nitrosating systems. Minimum purity: 99 per cent. Maximum dialkanolamine content: 0.5 per cent (applies to raw materials). Maximum N-nitrosodialkanolamine content:\n50 μg/kg (applies to raw materials). Keep in nitrite-free containers\n—\n62\nTrialkanolamines\n(a) non-rinse-off\n(b) other products\n(a) 2.5 per cent\n—\n(a) (b): Do not use with nitrosating systems. Minimum purity: 99 per cent. Maximum dialkanolamine content: 0.5 per cent (applies to raw materials). Maximum N-nitroso-dialkanolamine content: 50 μg/kg (applies to raw materials). Keep in nitrate-free containers\n—\n63\nStrontium hydroxide\npH-regulator in depilatory products\n3.5 per cent calculated as strontium\npH value not to exceed 12.7\nKeep out of reach of children. Avoid contact with the eyes\n64\nStrontium peroxide\nRinse-off hair care preparations for professional use\n4.5 per cent calculated as strontium in the ready-for-use preparation\nAll products must meet the hydrogen peroxide release requirements\nAvoid contact with eyes. Rinse eyes immediately if product comes into contact with them. For professional use only. Wear suitable gloves\n65\nBenzalkonium chloride (INN), bromide and saccharinate (eg. Cetalkonium chloride Stearalkonium chloride, Cetearalkonium bromide)\nHair care products rinsed off after use\n3 per cent calculated as benzalkonium chloride\nIn the finished product the concentration of benzalkonium chloride, bromide and saccharinate with an alkyl chain-length of C14 or less must not exceed 0.1 per cent calculated as benzalkonium chloride\nAvoid contact with the eyes\nOther products\n0.1 per cent calculated as benzalkonium chloride\n—\nAvoid contact with the eyes\n66\nPolyacrylamides\nBody-care leave-on products\n—\nMaximum residual acrylamide content 0.1 μg/kg\n—\nOther cosmetic products\n—\nMaximum residual acrylamide content 0.5 μg/kg\n—",
  "extent": null,
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/uksi/2003/835/schedule/4/part/I",
    "retrieved_at": "2026-10-29T06:27:30.309640+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}