# The Cosmetic Products (Safety) Regulations 2004, Part 1

Extent: E+W+S+N.I.

Part 1 of this Schedule lists the alternative methods validated by the European Centre for the Validation of Alternative Methods (“ECVAM”) which are necessary to meet the requirements of these Regulations and which are listed in Annex V to Council Directive 67/548/EEC of 27th June 1967 on the approximation of laws, regulations and administrative provisions relating to classification, packaging and labelling of dangerous substances .
The reference number given in the second column of the table in Part 1 refers to the reference number under which the type of test is listed in Annex V to Directive 67/548/EEC.
Entry Number
Reference Number
Type of Test (toxicological endpoint)
Alternative Test Method
Date after which this method is required to be used
1
B40
Skin corrosion
Rat skin TER assay
11.9.04
2
B40
Skin corrosion
Human skin model assay
11.9.04
3
B41
Phototoxicity
In vitro 3T3 NRU phototoxicity test
11.9.04

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Source: https://www.legislation.gov.uk/uksi/2004/2152/schedule/12/part/1 (the official version)
Page: https://openlegislation.uk/cosmetic-products-safety-regulations-2004/schedule-12/part-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.