# The Controlled Drugs (Drug Precursors) (Amendment and Revocation) Regulations 2026, Regulation 6: Amendment of Council Regulation (EC) 111/2005


(1) Council Regulation (EC) 111/2005 of 22 December 2004 laying down rules for the monitoring of trade between the Union and third countries in drug precursors is amended as follows.
(2) In Article 1 (subject matter)—
(a) for “the United Kingdom” substitute in both places it occurs “Great Britain”;
(b) in both places in occurs after “third countries” insert “or Northern Ireland”.
(3) In Article 2 (definitions)—
(a) in paragraphs (c), (d) and (e), for “the United Kingdom”, in each place it occurs substitute “Great Britain”;
(b) for paragraph (j) substitute—
“(j) ‘natural product’ means—
(i) an organism or a part thereof, in any form; or
(ii) a naturally occurring substance which is unprocessed or processed only by manual, mechanical or gravitational means, by dissolution in water, by flotation, by extraction with water, by steam distillation or by heating solely to remove water, or which is extracted from air by any means.”.
(4) In Article 6 (licensing) in paragraph (1), for “the United Kingdom” substitute “Great Britain”.
(5) In Article 7 (registration) in paragraph (1) for “the United Kingdom” substitute “Great Britain”.
(6) In Article 8 (demonstration of licit purposes) in paragraphs (1) and (2) for “the United Kingdom” substitute “Great Britain”.
(7) In Article 9 (provision of information) in paragraph (1) for “the United Kingdom” substitute “Great Britain”.
(8) In Article 10 (guidelines) in paragraph (1) for “the United Kingdom” substitute “Great Britain”.
(9) In Article 11 (pre-export notification)—
(a) other than in the third place it occurs in paragraph 1 in each place it occurs after “country of destination” insert “or Northern Ireland”;
(b) in the second place it occurs in paragraph 1 after “countries of destination” insert “which may include Northern Ireland,”;
(c) in paragraph 2 after “in the third country” insert “or Northern Ireland”.
(10) In Article 12 (export authorisation) in paragraph (1) for “the United Kingdom” substitute “Great Britain”.
(11) In Article 13 (application for export authorisation) in paragraph 1—
(a) in sub-paragraph (a) after “in the third country” insert “or Northern Ireland”;
(b) in sub-paragraph (d)—
(i) for “United Kingdom” substitute “Great Britain”;
(ii) after “importing country” insert “or Northern Ireland”;
(c) in sub-paragraph (e) after “the country of destination” insert “or Northern Ireland”.
(12) In Article 14 (presentation of export authorisation at point of exit)—
(a) in paragraphs (1) and (2) in each place it occurs for “the United Kingdom” substitute “Great Britain”;
(b) in paragraph (2) after “to the third country of destination insert “or Northern Ireland”.
(13) In Article 15 (refusal of export authorisation) in sub-paragraph (c) after “the country of destination” insert “or Northern Ireland”.
(14) In Article 17 (authorisation of exports)—
(a) after “third country” in the second and third place it occurs insert “or the competent authorities of Northern Ireland”;
(b) for “the United Kingdom” in the second place it occurs substitute “Great Britain”.
(15) In Article 18 (period of validity of export authorisation) for “the United Kingdom” substitute “Great Britain”.
(16) In Article 20 (import authorisation) for “the United Kingdom” substitute “Great Britain”.
(17) In Article 21 (application for import authorisation) after “of the third country” insert “or Northern Ireland”.
(18) In Article 22 (presentation of import authorisation) for “the United Kingdom” substitute “Great Britain.”.
(19) In Article 25 (period of validity of import authorisation) for “the United Kingdom” substitute “Great Britain.”.
(20) In Article 26 (powers of competent authority)—
(a) in paragraphs 1 and 3a for “the United Kingdom” substitute “Great Britain”;
(b) in paragraph 5 after the first sentence insert “Such fees shall be prescribed in regulations made by the Secretary of State.”.
(21) In Article 28 (delegated acts to ensure effective monitoring of trade)—
(a) for “the United Kingdom” substitute “Great Britain”;
(b) after “third countries” insert “or Northern Ireland”.
(22) Article 30a (delegated acts) after “Annex hereto” insert “to adapt”.
(23) Omit Article 33 (processing of personal data).
(24) In the Annex—
(a) for the table headed “Category 1” substitute—
Substance
CN designation (if different)
CN Code (1)
CAS No (2)
1-Phenyl-2-propanone
Phenylacetone
2914 31 00
103-79-7
Diethyl (phenylacetyl) propanedioate (also referred to as DEPAPD)
2918 30 00
20320-59-6
Methyl alpha-phenylacetoacetate (also referred to as MAPA)
2918 30 00
16648-44-5
Ethyl alpha-phenylacetoacetate (also referred to as EAPA) (4)
Ex 2918 30 00
5413-05-8
2-methyl-3-phenyloxirane-2-carboxylic acid (also referred to as BMK glycidic acid) (6)
2918 99 90
25547-51-7
N-acetylanthranilic acid
2-Acetamidobenzoic acid
2924 23 00
89-52-1
Alpha-phenylacetoacetamide (also referred to as APAA)
2924 29 70
4433-77-6
Alpha-phenylacetoacetonitrile (also referred to as APAAN)
2926 40 00
4468-48-8
Isosafrol (cis+trans)
2932 91 00
120-58-1
3,4-Methylenedioxyphenylpropan-2-one
1-(1,3-Benzodioxol-5-yl)propan-2-one
2932 92 00
4676-39-5
Piperonal
2932 93 00
120-57-0
Safrole
2932 94 00
94-59-7
Methyl 3-oxo-2-(3,4-methylenedioxyphenyl)butanoate (also referred to as MAMDPA) (5)
Methyl 3-oxo-2-(3,4-methylenedioxyphenyl)butanoate
Ex 2932 99 00
1369021-80-6
3-(1,3-benzodioxol-5-yl)-2-methyl-oxirane-2-carboxylic acid (also referred to as PMK glycidic acid) (7)
2932 99 00
2167189-50-4
Isopropylidene (2-(3,4-methylenedioxyphenyl)acetyl)malonate (also referred to as IMDPAM) (8)
IMDPAM
2932 99 00
N-phenyl-1-(2-phenylethyl)piperidin-4-amine
4-anilino-N- phenethylpiperidine (ANPP)
2933 36 00
21409-26-7
1-(2-phenylethyl)piperidin-4-one
N-phenethyl-4-piperidone (NPP)
2933 37 00
39742-60-4
N-phenylpiperidin-4-amine (also referred to as 4-AP)
2933 39 99
23056-29-3
Tert-butyl 4-anilinopiperidine-1-carboxylate (also referred to as 1-boc-4-AP)
2933 39 99
125541-22-2
N-phenyl-N-(piperidin-4-yl)propanamide (also referred to as norfentanyl)
2933 39 99
1609-66-1
4-piperidone
Piperidin-4-one
2933 39 99
41661-47-6
1-boc-4-piperidone
tert-butyl 4-oxopiperidine-1-carboxylate
2933 39 99
79099-07-3
Ephedrine
2939 41 00
299-42-3
Pseudoephedrine
2939 42 00
90-82-4
Norephedrine
>2939 44 00
14838-15-4
Ergometrine
2939 61 00
60-79-7
Ergotamine
2939 62 00
113-15-5
Lysergic acid
2939 63 00
82-58-6
(1R,2S)-(-)-chloroephedrine
2939 79 90
110925-64-9
(1S,2R)-(+)-chloroephedrine
2939 79 90
1384199-95-4
(1S,2S)-(+)-chloropseudoephedrine
2939 79 90
73393-61-0
(1R,2R)-(-)-chloropseudoephedrine
2939 79 90
771434-80-1
The stereoisomeric forms of the substances listed in this Category not being cathine (3) whenever the existence of such forms is possible.
The salts of the substances listed in this Category whenever the existence of such salts is possible and not being the salts of cathine.
(1) OJ No. L 290, 28.10.2002, p. 1.
(2) The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.
(3) Also named (+)-norpseudoephedrine, CN code 2939 43 00, CAS No 492-39-7.
(4)Also known as ethyl 3-oxo-2-phenylbutanoate, according to The International Union of Pure and Applied Chemistry (IUPAC).
(5) Also known as methyl 2-(2H-1,3-benzodioxol-5-yl)-3-oxobutanoate, according to IUPAC.
(6)And its ethyl, methyl (CAS No 80532-66-7), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as BMK glycidic acid.
(7)And its ethyl (CAS No 28578-16-7), methyl (CAS No 13605-48-6), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as PMK glycidic acid.
(8)Also known as 5-[2-(1,3-benzodioxol-5-yl)acetyl]–2,2-dimethyl–1,3-dioxane–4,6-dione, according to IUPAC.
(b) for the table headed “Category 2” substitute—
Substance
CN designation (if different)
CN Code (1)
CAS No (2)
Red phosphorus
2804 70 10
7723-14-0
Acetic anhydride
2915 24 00
108-24-7
Phenylacetic acid
2916 34 00
103-82-2
Anthranilic acid
2922 43 00
118-92-3
Piperidine
2933 32 00
110-89-4
Potassium permanganate
2841 61 00
7722-64-7
The salts of the substances listed in this Category whenever the existence of such salts is possible.
(1) OJ No. L 290, 28.10.2002, p. 1.
(2) The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.

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Source: https://www.legislation.gov.uk/ukdsi/2026/9780348279917/regulation/6 (the official version)
Page: https://openlegislation.uk/draft-controlled-drugs-drug-precursors-amendment-and-revocation-regulations-2026/regulation-6
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.