{
  "url": "https://openlegislation.uk/eu-decision-2006-437/annex/chapter-XIV/division-4",
  "json_url": "https://openlegislation.uk/eu-decision-2006-437/annex/chapter-XIV/division-4.json",
  "legislation": "eudn/2006/437",
  "legislation_title": "Commission Decision of 4 August 2006 approving a Diagnostic Manual for avian influenza as provided for in Council Directive 2005/94/EC (notified under document number C(2006) 3477) (Text with EEA relevance) (2006/437/EC)",
  "legislation_url": "https://openlegislation.uk/eu-decision-2006-437",
  "path": "annex/chapter/XIV/division/4",
  "kind": "division",
  "number": "4",
  "heading": "Requirements for Laboratories (containment levels 1 to 4)",
  "text": "In accordance with Directive 2000/54/EC of the European Parliament and of the Council of 18 September 2000 on the protection of workers from risks related to exposure to biological agents at work (seventh individual Directive within the meaning of Article 16(1) of Directive 89/391/EEC) (OJ L 262, 17.10.2000, p. 21), Directive 90/219/EEC and European Norms: EN 12128; EN 12740; EN 12741.\nContainment measures\nContainment level\n1\n2\n3\n4\nLaboratory suite: isolation\nno\nyes\nyes\nyes\nLaboratories separated by doors\nno\nyes\nyes\nyes\nAn observation window or alternative must be present so that occupants can be seen\noptional\noptional\noptional\nyes\nHand washing facilities must be provided for personnel\nyes\nyes\nyes\nyes\nDisinfecting facilities (hands) must be provided\noptional\nyes\nyes\nyes\nRestricted access\nno\nyes\nyes\nyes\nSpecific measures to control aerosol\nno\nYes\nminimise\nYes\nprevent\nYes\nprevent\nBiohazard sign on the door\nno\nyes\nyes\nyes\nShower\nno\nno\noptional\nyes\nEye irrigation\nyes\nyes\nyes\nyes\nLaboratory: sealable for fumigation\nno\nno\nyes\nyes\nSurfaces resistant to water, acids, alkalis, solvents, disinfectants, decontamination agents and easy to clean\nYes (bench)\nYes (bench)\nYes (bench, floor)\nYes (bench, floor)\nEntry to lab via airlock\nno\nno\noptional\nyes\nNegative pressure relative to the pressure of the immediate environment\nno\nno\noptional\nyes\nExtract and input air from laboratory must be HEPA-filtered\nno\nno\nyes (extract air)\nyes\nAutoclave\non site\nin the building\nen suite\nin lab, double ended\nProtective clothing\nSuitable protective clothing\nSuitable protective clothing\nSuitable protective clothing (optional footwear)\nComplete change of clothing\nGloves\nno\noptional\nyes\nyes\nEfficient vector control (e.g. for rodents and insects)\noptional\nyes\nyes\nyes\nSafe Storage of a biological agent\nyes\nyes\nyes\nyes\nLaboratory to contain its own equipment\nno\nno\nRecom-mended\nyes\nThere are additional European Norms which deal with the management and organisation of laboratories.\nThere are other national and international regulations and recommendations which must be followed. The WHO has published its Laboratory Biosafety Manual 3rd Edition on its website:\nhttp://www.who.int/csr/resources/publications/biosafety/WHO_CDS_CSR_LYO_2004_11/en/",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudn/2006/437/annex/chapter/XIV/division/4",
    "retrieved_at": "2026-11-01T15:17:33.742537+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}