Division Laboratory criteria
United Kingdom
At least one of the following three:
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Isolation of Shigatoxin/Verotoxin (STEC/VTEC) producing E. coli
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Detection of stx1 or stx2 gene(s) nucleic acid
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Detection of free shigatoxins.
Only for HUS the following can be used as laboratory criterion to confirm STEC/VTEC:
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E. coli serogroups specific antibody response
Isolation and additional ischaracterisation by serotype, phage type, eae genes, and subtypes of stx1/stx2 should be performed if possible