Division 2 In Annex C to Directive 64/432/EEC point 4.1 is replaced by the following:

‘4.1.

Tasks and responsibilities

National reference laboratories designated in accordance with Article 6a shall be responsible for:

1. (a)

   the approval of the results of the validation studies demonstrating the reliability of the test method used in the Member State;

2. (b)

   determination of the maximum number of samples to be pooled in ELISA kits used;

3. (c)

   calibration of working standards as referred to in point 2.1.6;

4. (d)

   quality checks of all antigens and ELISA kits batches used in the Member State;

5. (e)

   following recommendations of, and cooperating with the Community reference laboratory for brucellosis.’