# Commission Implementing Decision of 8 August 2012 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council (notified under document C(2012) 5538) (Text with EEA relevance) (2012/506/EU), Division: CNS-MEN: Meningitis or ventriculitis

Extent: E+W+S+N.I.

Meningitis or ventriculitis must meet at least one of the following criteria:
Patient has organisms cultured from cerebrospinal fluid (CSF)
Patient has at least one of the following signs or symptoms with no other recognised cause: fever (> 38 °C), headache, stiff neck, meningeal signs, cranial nerve signs, or irritability
AND at least one of the following:
increased white cells, elevated protein, and/or decreased glucose in CSF
organisms seen on Gram’s stain of CSF
organisms cultured from blood
positive antigen test of CSF, blood, or urine
diagnostic single antibody titer (IgM) or four-fold increase in paired sera (IgG) for pathogen
AND if diagnosis is made antemortem, physician institutes appropriate antimicrobial therapy.

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Source: https://www.legislation.gov.uk/eudn/2012/506/annex/division/3/division/3.1/division/3.1.3/division/2 (the official version)
Page: https://openlegislation.uk/eu-decision-2012-506/annex/division-3/division-3.1/division-3.1.3/division-2
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.