{
  "url": "https://openlegislation.uk/eu-decision-2014-423/annex",
  "json_url": "https://openlegislation.uk/eu-decision-2014-423/annex.json",
  "legislation": "eudn/2014/423",
  "legislation_title": "Commission Implementing Decision of 1 July 2014 authorising the placing on the market of citicoline as a novel food ingredient under Regulation (EC) No 258/97 of the European Parliament and of the Council (notified under document C(2014) 4252) (Only the German text is authentic) (2014/423/EU)",
  "legislation_url": "https://openlegislation.uk/eu-decision-2014-423",
  "path": "annex",
  "kind": "annex",
  "number": null,
  "heading": "SPECIFICATION OF CITICOLINE",
  "text": "Definition Citicoline is composed of cytosine, ribose, pyrophosphate and choline.\nChemical name: Choline cytidine 5′-pyrophosphate, Cytidine 5′-(trihydrogen diphosphate) P′-[2-(trimethylammonio)ethyl]ester inner salt\nChemical formula: C14H26N4O11P2\nMolecular weight: 488,32 g/mol\nDescription White crystalline powder.\nIdentification CAS No\n987-78-0\npH (sample solution of 1 %)\n2,5-3,5\nPurity Assay value\nNot less than 98 % of dry matter\nLoss on drying (100 °C for 4 hours)\nNot more than 5,0 %\nAmmonium\nNot more than 0,05 %\nTotal heavy metals (as Pb)\nNot more than 10 ppm\nArsenic\nNot more than 2 ppm\nFree phosphoric acids\nNot more than 0,1 %\n5′-Cytidylic acid\nNot more than 1,0 %\nMicrobiological criteria Total plate count\nNot more than 1 000 cfu/g\nYeast and moulds\nNot more than 100 cfu/g\nEscherichia coli\nAbsent in 1 g",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudn/2014/423/annex",
    "retrieved_at": "2026-11-01T15:14:43.501616+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}