Division Laboratory Criteria (HIV)
United Kingdom
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Adults, adolescents and children aged ≥ 18 months
At least one of the following three:
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Positive result of a HIV screening antibody test or a combined screening test (HIV antibody and HIV p24 antigen) confirmed by a more specific antibody test (for example, Western blot);
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Positive result of 2 EIA antibody test confirmed by a positive result of a further EIA test;
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Positive results on two separate specimens from at least one of the following three:
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Detection of HIV nucleic acid (HIV-RNA, HIV-DNA);
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Demonstration of HIV by HIV p24 antigen test, including neutralisation assay;
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Isolation of HIV.
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Children aged < 18 months
Positive results on two separate specimens (excluding cord blood) from at least one of the following three:
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Isolation of HIV;
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Detection of HIV nucleic acid (HIV-RNA, HIV-DNA);
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Demonstration of HIV by HIV p24 antigen test, including neutralisation assay in a child ≥ 1 month of age.
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