Division Laboratory Criteria

At least one of the following four:

• Isolation of Lyssa virus from a clinical specimen

• Detection of Lyssa virus nucleic acid in a clinical specimen (for example, saliva or brain tissue)

• Detection of viral antigens by a DFA in a clinical specimen

• Lyssa virus specific antibody response by virus neutralization assay in serum or CSF

Laboratory results need to be interpreted according to the vaccination or immunization status