{
  "url": "https://openlegislation.uk/eu-decision-2018-945/annex-II/division-4/division-4.1/division-4.1.3/division-1",
  "json_url": "https://openlegislation.uk/eu-decision-2018-945/annex-II/division-4/division-4.1/division-4.1.3/division-1.json",
  "legislation": "eudn/2018/945",
  "legislation_title": "Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-decision-2018-945",
  "path": "annex/II/division/4/division/4.1/division/4.1.3/division/1",
  "kind": "division",
  "number": null,
  "heading": "CNS-IC: Intracranial infection (brain abscess, subdural or epidural infection, encephalitis)",
  "text": "Intracranial infection must meet at least one of the following criteria:\nPatient has organisms cultured from brain tissue or dura\nPatient has an abscess or evidence of intracranial infection seen during a surgical operation or histopathologic examination\nPatient has at least 2 of the following signs or symptoms with no other recognized cause: headache, dizziness, fever (> 38 °C), localizing neurologic signs, changing level of consciousness, or confusion\nAND at least 1 of the following:\norganisms seen on microscopic examination of brain or abscess tissue obtained by needle aspiration or by biopsy during a surgical operation or autopsy\npositive antigen test on blood or urine\nradiographic evidence of infection (for example, abnormal findings on ultrasound, CT scan, MRI, radionuclide brain scan, or arteriogram)\ndiagnostic single antibody titre (IgM) or 4-fold increase in paired sera (IgG) for pathogen\nAND if diagnosis is made antemortem, physician institutes appropriate antimicrobial therapy.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudn/2018/945/annex/II/division/4/division/4.1/division/4.1.3/division/1",
    "retrieved_at": "2026-11-01T15:13:03.598650+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}