# Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions (Text with EEA relevance), Division: CVS-ENDO: Endocarditis

Extent: E+W+S+N.I.

Endocarditis of a natural or prosthetic heart valve must meet at least one of the following criteria:
Patient has organisms cultured from valve or vegetation
Patient has two or more of the following signs or symptoms with no other recognized cause: fever (> 38 °C), new or changing murmur, embolic phenomena, skin manifestations (for example, petechiae, splinter hemorrhages, painful subcutaneous nodules), congestive heart failure, or cardiac conduction abnormality
AND at least one of the following:
organisms cultured from two or more blood cultures
organisms seen on Gram's stain of valve when culture is negative or not done
valvular vegetation seen during a surgical operation or autopsy
positive antigen test on blood or urine (for example, Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, or Group B Streptococcus)
evidence of new vegetation seen on echocardiogram
AND if diagnosis is made antemortem, physician institutes appropriate antimicrobial therapy

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Source: https://www.legislation.gov.uk/eudn/2018/945/annex/II/division/4/division/4.1/division/4.1.5/division/2 (the official version)
Page: https://openlegislation.uk/eu-decision-2018-945/annex-II/division-4/division-4.1/division-4.1.5/division-2
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.