Division 10.7 Maintenance of colonies of established genetically altered animals, not used in other procedures

This contains animals required for the maintenance of colonies of genetically altered animals of established lines with an intended harmful phenotype and which have exhibited pain, suffering, distress or lasting harm as a consequence of the harmful genotype. The intended purpose which the line is being bred for is not recorded.

This category also includes genetically altered animals during maintenance of an established line, irrespective of whether the line is of non-harmful or harmful phenotype, and either of the following applies:

1. (a)

   the genotype has been confirmed using an invasive method, which was not carried out for the purposes of identification/marking of the animal, and the animal is killed without further use;

2. (b)

   the animals are of unsuitable genotype, confirmed using an invasive method, which was not carried out for the purposes of identification/marking of the animal.

This category also includes re-derivation where it is done solely for scientific purposes (that is to say not to benefit health/welfare of colony) during maintenance of an established line, and animals used for embryo transfer and vasectomy.

This excludes all animals needed for the creation of a new genetically altered line and those used in other procedures (that is to say other than creation/maintenance).