Division Preliminary noteF1
United Kingdom
The measures contained in this Annex shall be applied according to the nature of the activities, the assessment of risk to workers, and the nature of the biological agent concerned.
In the table, ‘ Recommended ’ means that the measures should in principle be applied, unless the results of the assessment referred to in Article 3(2) indicate otherwise.
| HEPA: High efficiency particulate air | |||
| Airlock: Entry must be through an airlock which is a chamber isolated from the laboratory. The clean side of the airlock must be separated from the restricted side by changing or showering facilities and preferably by interlocking doors. | |||
| A. Containment measures | B. Containment levels | ||
|---|---|---|---|
| 2 | 3 | 4 | |
| Workplace | |||
| 1. The workplace is to be separated from any other activities in the same building | No | Recommended | Yes |
| 2. The workplace is to be sealable to permit fumigation | No | Recommended | Yes |
| Facilities | |||
| 3. Infected material including any animal is to be handled in a safety cabinet or isolation or other suitable containment | Where appropriate | Yes, where infection is by airborne route | Yes |
| Equipment | |||
| 4. Input air and extract air to the workplace are to be filtered using (HEPA f1 ) or likewise | No | Yes, on extract air | Yes, on input and extract air |
| 5. The workplace is to be maintained at an air pressure negative to atmosphere | No | Recommended | Yes |
| 6. Surfaces impervious to water and easy to clean | Yes, for bench and floor | Yes, for bench, floor and other surfaces determined by risk assessment | Yes, for bench, walls, floor and ceiling |
| 7. Surfaces resistant to acids, alkalis, solvents, disinfectants | Recommended | Yes | Yes |
| System of work | |||
| 8. Access is to be restricted to nominated workers only | Recommended | Yes | Yes, via airlock f2 |
| 9. Efficient vector control, for example rodents and insects | Recommended | Yes | Yes |
| 10. Specified disinfection procedures | Yes | Yes | Yes |
| 11. Safe storage of a biological agent | Yes | Yes | Yes, secure storage |
| 12. Personnel should shower before leaving the contained area | No | Recommended | Recommended |
| Waste | |||
| 13. Validated inactivation process for the safe disposal of animal carcases | Recommended | Yes, on or off site | Yes, on site |
| Other measures | |||
| 14. A laboratory is to contain its own equipment | No | Recommended | Yes |
| 15. An observation window, or, alternative, is to be present, so that occupants can be seen | Recommended | Recommended | Yes |
Annotations
Textual amendments
Footnotes
- f1
-
HEPA: High efficiency particulate air
- f2
-
Airlock: Entry must be through an airlock which is a chamber isolated from the laboratory. The clean side of the airlock must be separated from the restricted side by changing or showering facilities and preferably by interlocking doors.