{
  "url": "https://openlegislation.uk/eu-directive-2001-18/annex-II/division-C/division-C.1/division-2",
  "json_url": "https://openlegislation.uk/eu-directive-2001-18/annex-II/division-C/division-C.1/division-2.json",
  "legislation": "eudr/2001/18",
  "legislation_title": "Directive 2001/18/EC of the European Parliament and of the Council of 12 March 2001 on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC",
  "legislation_url": "https://openlegislation.uk/eu-directive-2001-18",
  "path": "annex/II/division/C/division/C.1/division/2",
  "kind": "division",
  "number": "2",
  "heading": "Long-term adverse effects and cumulative long-term adverse effects in the e.r.a. of Part C notifications",
  "text": "Long-term effects of a GMO are effects resulting either from a delayed response by organisms or their progeny to long-term or chronic exposure to a GMO or from an extensive use of a GMO in time and space.\nThe identification and evaluation of the potential long-term adverse effects of a GMO on human health and on the environment shall take into account the following:\n(a) the long-term interactions of the GMO and the receiving environment;\n(b) the characteristics of the GMO which become important on a long-term basis;\n(c) data obtained from repeated deliberate releases or placings on the market of the GMO over a long period.\nThe identification and evaluation of the potential cumulative long-term adverse effects referred to in the introductory part of Annex II shall also take into account the GMOs deliberately released or placed on the market in the past.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Substituted by Commission Directive (EU) 2018/350 of 8 March 2018 amending Directive 2001/18/EC of the European Parliament and of the Council as regards the environmental risk assessment of genetically modified organisms."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudr/2001/18/annex/II/division/C/division/C.1/division/2",
    "retrieved_at": "2026-11-01T15:23:00.934371+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}