# Directive 2001/18/EC of the European Parliament and of the Council of 12 March 2001 on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC, Division 2: Long-term adverse effects and cumulative long-term adverse effects in the e.r.a. of Part C notifications

Extent: E+W+S+N.I.

Long-term effects of a GMO are effects resulting either from a delayed response by organisms or their progeny to long-term or chronic exposure to a GMO or from an extensive use of a GMO in time and space.
The identification and evaluation of the potential long-term adverse effects of a GMO on human health and on the environment shall take into account the following:
(a) the long-term interactions of the GMO and the receiving environment;
(b) the characteristics of the GMO which become important on a long-term basis;
(c) data obtained from repeated deliberate releases or placings on the market of the GMO over a long period.
The identification and evaluation of the potential cumulative long-term adverse effects referred to in the introductory part of Annex II shall also take into account the GMOs deliberately released or placed on the market in the past.

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Source: https://www.legislation.gov.uk/eudr/2001/18/annex/II/division/C/division/C.1/division/2 (the official version)
Page: https://openlegislation.uk/eu-directive-2001-18/annex-II/division-C/division-C.1/division-2
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.