# Commission Directive 2004/33/EC of 22 March 2004 implementing Directive 2002/98/EC of the European Parliament and of the Council as regards certain technical requirements for blood and blood components (Text with EEA relevance), Division 2.1: Permanent deferral criteria for donors of allogeneic donations

Extent: E+W+S+N.I.

Cardiovascular disease
Prospective donors with active or past serious cardiovascular disease, except congenital abnormalities with complete cure
Central nervous system disease
A history of serious CNS disease
Abnormal bleeding tendency
Prospective donors who give a history of a coagulopathy
Repeated episodes of syncope, or a history of convulsions
Other than childhood convulsions or where at least three years have elapsed since the date the donor last took anticonvulsant medication without any recurrence of convulsions
Gastrointestinal, genitourinary, haematological, immunological, metabolic, renal, or respiratory system diseases
Prospective donors with serious active, chronic, or relapsing disease
Diabetes
If being treated with insulin
Infectious diseases
Hepatitis B, except for HBsAg-negative persons who are demonstrated to be immune
Hepatitis C
HIV-1/2
HTLV I/II
Babesiosis (*)
Kala Azar (visceral leishmaniasis) (*)
Trypanosomiasis cruzi (Chagas' disease) (*)
Malignant diseases
Except in situ cancer with complete recovery
Transmissible spongiform encephalopathies (TSEs), (e.g. Creutzfeldt Jakob Disease, variant Creutzfeldt Jakob Disease)
Persons who have a family history which places them at risk of developing a TSE, or persons who have received a corneal or dura mater graft, or who have been treated in the past with medicines made from human pituitary glands. For variant Creutzfeldt Jacob disease, further precautionary measures may be recommended.
Intravenous (IV) or intramuscular (IM) drug use
Any history of non-prescribed IV or IM drug use, including body-building steroids or hormones
Xenotransplant recipients
Sexual behaviour
Persons whose sexual behaviour puts them at high risk of acquiring severe infectious diseases that can be transmitted by blood

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Source: https://www.legislation.gov.uk/eudr/2004/33/annex/III/division/2/division/2.1 (the official version)
Page: https://openlegislation.uk/eu-directive-2004-33/annex-III/division-2/division-2.1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.