{
  "url": "https://openlegislation.uk/eu-directive-2004-73/annex-2I/division-C.23/division-1/division-1.5",
  "json_url": "https://openlegislation.uk/eu-directive-2004-73/annex-2I/division-C.23/division-1/division-1.5.json",
  "legislation": "eudr/2004/73",
  "legislation_title": "Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the twenty-ninth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-directive-2004-73",
  "path": "annex/2I/division/C.23/division/1/division/1.5",
  "kind": "division",
  "number": "1.5",
  "heading": "INFORMATION ON THE TEST SUBSTANCE",
  "text": "Non-labelled or labelled test substance can be used to measure the rate of transformation. Labelled material is required for studying the pathway of transformation and for establishing a mass balance. 14C-labelling is recommended but the use of other isotopes, such as 13C, 15N, 3H, 32P, may also be useful. As far as possible, the label should be positioned in the most stable part(s) of the molecule. The purity of the test substance should be at least 95 %.\nBefore carrying out a test on aerobic and anaerobic transformation in soil, the following information on the test substance should be available:\n(a) solubility in water (Method A.6)\n(b) solubility in organic solvents;\n(c) vapour pressure (Method A.4) and Henry's law constant;\n(d) n-octanol/water partition coefficient (Method A.8);\n(e) chemical stability in dark (hydrolysis) (Method C.7);\n(f) pKa if a molecule is liable to protonation or deprotonation [OECD Guideline 112 ] (16).\nOther useful information may include data on toxicity of the test substance to soil micro-organisms [Testing Methods C.21 and C.22] (16).\nAnalytical methods (including extraction and clean-up methods) for quantification and identification of the test substance and its transformation products should be available.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "footnote",
      "label": "f1",
      "text": "For example, if the test substance contains one ring, labelling on this ring is required; if the test substance contains two or more rings, separate studies may be needed to evaluate the fate of each labelled ring and to obtain suitable information on formation of transformation products."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudr/2004/73/annex/2I/division/C.23/division/1/division/1.5",
    "retrieved_at": "2026-11-01T15:22:47.605967+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}