{
  "url": "https://openlegislation.uk/eu-directive-2004-73/annex-n4/division-ANNEX/division-1",
  "json_url": "https://openlegislation.uk/eu-directive-2004-73/annex-n4/division-ANNEX/division-1.json",
  "legislation": "eudr/2004/73",
  "legislation_title": "Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the twenty-ninth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-directive-2004-73",
  "path": "annex/n4/division/ANNEX/division/1",
  "kind": "division",
  "number": null,
  "heading": "GENERAL REMARKS",
  "text": "For each starting dose, the respective testing schemes as included in this Annex outline the procedure to be followed.\nAnnex 1 a: Starting dose is 5 mg/kg bw\nAnnex 1 b: Starting dose is 50 mg/kg bw\nAnnex 1 c: Starting dose is: 300 mg/kg bw\nAnnex 1 d: Starting dose is: 2000 mg/kg bw\nDepending on the number of humanely killed or dead animals, the test procedure follows the indicated arrows.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudr/2004/73/annex/n4/division/ANNEX/division/1",
    "retrieved_at": "2026-11-01T15:22:47.605967+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}