# Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the twenty-ninth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Text with EEA relevance), Division: GENERAL REMARKS

Extent: E+W+S+N.I.

For each starting dose, the respective testing schemes as included in this Annex outline the procedure to be followed.
Annex 1 a: Starting dose is 5 mg/kg bw
Annex 1 b: Starting dose is 50 mg/kg bw
Annex 1 c: Starting dose is: 300 mg/kg bw
Annex 1 d: Starting dose is: 2000 mg/kg bw
Depending on the number of humanely killed or dead animals, the test procedure follows the indicated arrows.

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Source: https://www.legislation.gov.uk/eudr/2004/73/annex/n4/division/ANNEX/division/1 (the official version)
Page: https://openlegislation.uk/eu-directive-2004-73/annex-n4/division-ANNEX/division-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.