# Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the twenty-ninth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Text with EEA relevance), Division 1.6.6: Observations of the dams

Extent: E+W+S+N.I.

Clinical observations should be made and recorded at least once a day, preferably at the same time(s) each day taking into consideration the peak period of anticipated effects after dosing. The condition of the animals should be recorded including mortality, moribundity, pertinent behavioural changes, and all signs of overt toxicity.

---
Source: https://www.legislation.gov.uk/eudr/2004/73/annex/n7/division/B.31/division/1/division/1.6/division/1.6.6 (the official version)
Page: https://openlegislation.uk/eu-directive-2004-73/annex-n7/division-B.31/division-1/division-1.6/division-1.6.6
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.