# Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the twenty-ninth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Text with EEA relevance), Division 1.3.1: Selection of animal species

Extent: E+W+S+N.I.

The rat is the preferred species for testing. If other species are used, justification should be given and appropriate modifications will be necessary. Strains with low fecundity or well-known high incidence of developmental defects should not be used. At the commencement of the study, the weight variation of animals used should be minimal and not exceed 20 % of the mean weight of each sex.

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Source: https://www.legislation.gov.uk/eudr/2004/73/annex/n8/division/B.35/division/1/division/1.3/division/1.3.1 (the official version)
Page: https://openlegislation.uk/eu-directive-2004-73/annex-n8/division-B.35/division-1/division-1.3/division-1.3.1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.