{
  "url": "https://openlegislation.uk/eu-directive-2005-25/annex/division-B/division-2/division-2.2/division-2.2.1/division-2.2.1.2",
  "json_url": "https://openlegislation.uk/eu-directive-2005-25/annex/division-B/division-2/division-2.2/division-2.2.1/division-2.2.1.2.json",
  "legislation": "eudr/2005/25",
  "legislation_title": "Council Directive 2005/25/EC of 14 March 2005 amending Annex VI to Directive 91/414/EEC as regards plant protection products containing micro-organisms (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-directive-2005-25",
  "path": "annex/division/B/division/2/division/2.2/division/2.2.1/division/2.2.1.2",
  "kind": "division",
  "number": "2.2.1.2",
  "heading": "The ability of micro-organisms to adapt to the environment must be evaluated. In particular, Member States must take account of the following principles:",
  "text": "(a) depending on the conditions (e.g. availability of substrates for growth and metabolism) micro-organisms can switch on or off the expression of given phenotypic traits;\n(b) the microbial strains most adapted to the environment can survive and multiply better than the non-adapted strains. Adapted strains have a selective advantage and can form the majority within a population after a number of generations;\n(c) the relatively rapid multiplication of micro-organisms leads to a higher frequency of mutations. If a mutation is promoting survival in the environment, the mutant strain can become dominant;\n(d) the properties of viruses, in particular, can change rapidly, including their virulence.\nTherefore, where appropriate, information on the genetic stability of the micro-organism under the environmental conditions of proposed use must be evaluated, as well as information on the micro-organism's capacity to transfer genetic material to other organisms and information on the stability of encoded traits.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eudr/2005/25/annex/division/B/division/2/division/2.2/division/2.2.1/division/2.2.1.2",
    "retrieved_at": "2026-11-01T15:22:44.100508+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}