# Directive 2009/41/EC of the European Parliament and of the Council of 6 May 2009 on the contained use of genetically modified micro-organisms (Recast) (Text with EEA relevance), Division 1: The following should be considered as potentially harmful effects:

Extent: E+W+S+N.I.

disease to humans, including allergenic or toxic effects,
disease to animals or plants,
deleterious effects due to the impossibility of treating a disease or providing an effective prophylaxis,
deleterious effects due to establishment or dissemination in the environment,
deleterious effects due to the natural transfer of inserted genetic material to other organisms.

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Source: https://www.legislation.gov.uk/eudr/2009/41/annex/III/division/A/division/1 (the official version)
Page: https://openlegislation.uk/eu-directive-2009-41/annex-III/division-A/division-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.