Division 2 The assessment referred to in Article 4(2) should be based on the following:

the identification of any potentially harmful effects, in particular those associated with:

1. (i)

   the recipient micro-organism;

2. (ii)

   the genetic material inserted (originating from the donor organism);

3. (iii)

   the vector;

4. (iv)

   the donor micro-organism (as long as the donor micro-organism is used during the operation);

5. (v)

   the resulting GMM;

the characteristics of the activity;

the severity of the potentially harmful effects;

the likelihood of the potentially harmful effects being realised.