{
  "url": "https://openlegislation.uk/eu-regulation-1998-1570/annex",
  "json_url": "https://openlegislation.uk/eu-regulation-1998-1570/annex.json",
  "legislation": "eur/1998/1570",
  "legislation_title": "Commission Regulation (EC) No 1570/98 of 17 July 1998 amending Annexes I to IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-1998-1570",
  "path": "annex",
  "kind": "annex",
  "number": null,
  "heading": null,
  "text": "A.. Annex I to Regulation (EEC) No 2377/90 is amended as follows:\n1.. Anti-infectious agents\n1.1. Chemotherapeutics\n1.1.1. Sulfonamides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘All substances belonging to the sulfonamide group\nParent drug\nAll food producing species\n100 μg/kg\nMuscle\nThe combined total residues of all substances within the sulfonamide group should not exceed 100 μg/kg’\n100 μg/kg\nFat\n100 μg/kg\nLiver\n100 μg/kg\nKidney\nBovine, ovine, caprine\n100 μg/kg\nMilk\n1.1.2. Diamino pyrimidine derivates\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Baquiloprim\nBaquiloprim\nBovine\n10 μg/kg\nFat\n300 μg/kg\nLiver\n150 μg/kg\nKidney\n30 μg/kg\nMilk\nPorcine\n40 μg/kg\nSkin + fat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\nTrimethoprim\nTrimethoprim\nBovine\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n50 μg/kg\nMilk\nPorcine\n50 μg/kg\nMuscle\n50 μg/kg\nSkin + fat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\nEquidae\n100 μg/kg\nMuscle\n100 μg/kg\nFat\n100 μg/kg\nLiver\n100 μg/kg\nKidney\nPoultry not for use in animals from which eggs are produced for human consumption\n50 μg/kg\nMuscle\n50 μg/kg\nSkin + fat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\nFin fish\n50 μg/kg\nMuscle and skin in natural proportions’\n1.2. Antibiotics\n1.2.1. Penicillins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Amoxicyllin\nAmoxicyllin\nAll food producing species\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n4 μg/kg\nMilk\nAmpicillin\nAmpicillin\nAll food producing species\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n4 μg/kg\nMilk\nBenzylpenicillin\nBenzylpenicillin\nAll food producing species\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n4 μg/kg\nMilk\nCloxacillin\nCloxacillin\nAll food producing species\n300 μg/kg\nMuscle\n300 μg/kg\nFat\n300 μg/kg\nLiver\n300 μg/kg\nKidney\n30 μg/kg\nMilk\nOxacillin\nOxacillin\nAll food producing species\n300 μg/kg\nMuscle\n300 μg/kg\nFat\n300 μg/kg\nLiver\n300 μg/kg\nKidney\n30 μg/kg\nMilk\nPenethamate\nBenzylpenicillin\nBovine\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n4 μg/kg\nMilk’\n1.2.2. Cephalosporins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Cefazolin\nCefazolin\nBovine, ovine, caprine\n50 μg/kg\nMilk\nCefquinome\nCefquinome\nBovine\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n100 μg/kg\nLiver\n200 μg/kg\nKidney\n20 μg/kg\nMilk’\n1.2.3. Quinolones\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Danofloxacine\nDanofloxacine\nBovine (not for use in animals from which milk is produced for human consumption)\n200 μg/kg\nMuscle\n100 μg/kg\nFat\n400 μg/kg\nLiver\n400 μg/kg\nKidney\nChicken (not for use in animals from which eggs are produced for human consumption)\n200 μg/kg\nMuscle\n100 μg/kg\nSkin + fat\n400 μg/kg\nLiver\n400 μg/kg\nKidney\nDifloxacin\nDifloxacin\nChicken, turkey\n300 μg/kg\nMuscle\n400 μg/kg\nSkin + fat\n1 900 μg/kg\nLiver\n600 μg/kg\nKidney\nEnrofloxacin\nSum of enrofloxacin and ciprofloxacin\nBovine, porcine, poultry\n30 μg/kg\nMuscle\n30 μg/kg\nLiver\n30 μg/kg\nKidney\nSarafloxacin\nSarafloxacin\nChicken\n10 μg/kg\nSkin + fat\n100 μg/kg\nLiver’\n1.2.4. Macrolides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Spiramycin\nSum of spiramycin and neospiramycin\nBovine\n200 μg/kg\nMuscle\n300 μg/kg\nFat\n300 μg/kg\nLiver\n300 μg/kg\nKidley\n200 μg/kg\nMilk\nChicken\n200 μg/kg\nMuscle\n300 μg/kg\nSkin + fat\n400 μg/kg\nLiver\nTilmicosin\nTilmicosin\nBovine, ovine, porcine\n1 000 μg/kg\nLiver\n1 000 μg/kg\nKidney\nOvine\n50 μg/kg\nMilk\nTylosin\nTylosin A\nBovine\n100 μg/kg\nMuscle\n100 μg/kg\nFat\n100 μg/kg\nLiver\n100 μg/kg\nKidney\n50 μg/kg\nMilk\nPorcine\n100 μg/kg\nMuscle\n100 μg/kg\nSkin + fat\n100 μg/kg\nLiver\n100 μg/kg\nKidney\nPoultry (not for use in hens producing eggs for human consumption)\n100 μg/kg\nMuscle\n100 μg/kg\nSkin + fat\n100 μg/kg\nLiver\n100 μg/kg\nKidney’\n1.2.5. Florfenicol and related compounds\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Florfenicol\nSum of florfenicol and its metabolites measured as florfenicol-amine\nBovine\n200 μg/kg\nMuscle\n3 000 μg/kg\nLiver\n300 μg/kg\nKidney’\n1.2.6. Tetracyclines\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Chlortetracycline\nSum of parent drug and its 4-epimer\nAll food producing species\n100 μg/kg\nMuscle\n300 μg/kg\nLiver\n600 μg/kg\nKidney\n100 μg/kg\nMilk\n200 μg/kg\nEggs\nDoxycycline\nDoxycycline\nBovine\n100 μg/kg\nMuscle\n300 μg/kg\nLiver\n600 μg/kg\nKidney\nPorcine, poultry\n100 μg/kg\nMuscle\n300 μg/kg\nSkin + fat\n300 μg/kg\nLiver\n600 μg/kg\nKidney\nOxytetracycline\nSum of parent drug and its 4-epimer\nAll food producing species\n100 μg/kg\nMuscle\n300 μg/kg\nLiver\n600 μg/kg\nKidney\n100 μg/kg\nMilk\n200 μg/kg\nEggs\nTetracycline\nSum of parent drug and its 4-epimer\nAll food producing species\n100 μg/kg\nMuscle\n300 μg/kg\nLiver\n600 μg/kg\nKidney\n100 μg/kg\nMilk\n200 μg/kg\nEggs’\n1.2.7. Thiamphenicol and related compounds\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Thiamphenicol\nThiamphenicol\nBovine\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n50 μg/kg\nMilk\nChicken (not for use in animals from which eggs are produced for human consumption)\n50 μg/kg\nMuscle\n50 μg/kg\nSkin + fat\n50 μg/kg\nLiver\n50 μg/kg\nKidney’\n2.. Antiparasitic agents\n2.1. Agents acting against endoparasites\n2.1.1. Salicylanilides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Closantel\nClosantel\nBovine\n1 000 μg/kg\nMuscle\n3 000 μg/kg\nFat\n1 000 μg/kg\nLiver\n3 000 μg/kg\nKidney\nOvine\n1 500 μg/kg\nMuscle\n2 000 μg/kg\nFat\n1 500 μg/kg\nLiver\n5 000 μg/kg\nKidney’\n2.1.2. Tatra-hydro-imidazoles (imidazolthiazoles)\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Levamisole\nLevamisole\nBovine, ovine, porcine, poultry\n10 μg/kg\nMuscle\n10 μg/kg\nFat\n100 μg/kg\nLiver\n10 μg/kg\nKidney’\n2.1.3. Benzimidazoles and pro-benzimidazoles\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Febantel\nSum of extractable residues which may be oxidised to oxfendazole sulphone\nBovine, ovine\n10 μg/kg\nMilk\nBovine, ovine, porcine, equidae\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n500 μg/kg\nLiver\n50 μg/kg\nKidney\nFenbendazole\nSum of extractable residues which may be oxidised to oxfendazole sulphone\nBovine, ovine\n10 μg/kg\nMilk\nBovine, ovine, porcine, equidae\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n500 μg/kg\nLiver\n50 μg/kg\nKidney\nFlubendazole\nSum of flubendazole and (2-amino 1H-benzimidazol-5-yl) (4-flurorophenyl)methanone\nPorcine, chicken, game birds\n50 μg/kg\nMuscle\n50 μg/kg\nSkin + fat\n400 μg/kg\nLiver\n300 μg/kg\nKidney\nFlubendazole\nChicken\n400 μg/kg\nEggs\nOxfendazole\nSum of extractable residues which may be oxidised to oxfendazole sulphone\nBovine, ovine\n10 μg/kg\nMilk\nBovine, ovine, porcine, equidae\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n500 μg/kg\nLiver\n50 μg/kg\nKidney\nOxibendazole\nOxibendazole\nPorcine\n100 μg/kg\nMuscle\n500 μg/kg\nSkin + fat\n200 μg/kg\nLiver\n100 μg/kg\nKidney\nThiabendazole\nSum of thiabendazole and 5-hydroxythiabendazole\nBovine\n100 μg/kg\nMuscle\n100 μg/kg\nFat\n100 μg/kg\nLiver\n100 μg/kg\nKidney\n100 μg/kg\nMilk\nTriclabendazole\nSum of extractable residues that may be oxidised to ketotriclaben-dazole\nBovine, ovine\n100 μg/kg\nMuscle\nNot for use in animals from which milk is produced for human consumption’\n100 μg/kg\nLiver\n100 μg/kg\nKidney\n2.2. Agents acting against ectoparasites\n2.2.1. Organophosphates\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Diazinon\nDiazinon\nBovine, ovine, caprine\n20 μg/kg\nMilk\nBovine, porcine, ovine, caprine\n20 μg/kg\nMuscle\n700 μg/kg\nFat\n20 μg/kg\nLiver\n20 μg/kg\nKidney’\n2.2.2. Formamidines\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Amitraz\nSum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz\nPorcine\n400 μg/kg\nSkin + fat\n200 μg/kg\nLiver\n200 μg/kg\nKidney’\n2.3. Agents acting against endo- and ectoparasites\n2.3.1. Avermectins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Abamectin\nAvermectin Bla\nBovine\n10 μg/kg\nFat\n20 μg/kg\nLiver\nDoramectin\nDoramectin\nBovine\n10 μg/kg\nMuscle\nNot for use in ovines from which milk is produced for human consumption’\n150 μg/kg\nFat\n100 μg/kg\nLiver\n30 μg/kg\nKidney\nPorcine, ovine\n20 μg/kg\nMuscle\n100 μg/kg\nFat\n50 μg/kg\nLiver\n30 μg/kg\nKidney\nEprinomectin\nEprinomectin Bla\nBovine\n30 μg/kg\nMuscle\n30 μg/kg\nFat\n600 μg/kg\nLiver\n100 μg/kg\nKidney\n30 μg/kg\nMilk\nIvermectin\n22,23-Dihydro-aver-mectin Bla\nBovine\n40 μg/kg\nFat\n100 μg/kg\nLiver\nPorcine, ovine, equidae\n20 μg/kg\nFat\n15 μg/kg\nLiver\nMoxidectin\nMoxidectin\nBovine, ovine\n50 μg/kg\nMuscle\n500 μg/kg\nFat\n100 μg/kg\nLiver\n50 μg/kg\nKidney\n3.. Agents acting on the nervous system\n3.2. Agents acting on the autonomic nervous system\n3.2.1. Anti-adrenergics\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Carazolol\nCarazolol\nPorcine\n5 μg/kg\nMuscle\n5 μg/kg\nSkin + fat\n25 μg/kg\nLiver\n25 μg/kg\nKidney’\n4.. Anti-infammatory agents\n4.1. Nonsteroidal anti-infammatory agents\n4.1.1. Arylpropionic acid derivative\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Vedaprofen\nVedaprofen\nEquidae\n50 μg/kg\nMuscle\n20 μg/kg\nFat\n100 μg/kg\nLiver\n1 000 μg/kg\nKidney’\n4.1.2. Fenamate group derivates\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Tolfenamic acid\nTolfenamic acid\nBovine\n50 μg/kg\nMuscle\n400 μg/kg\nLiver\n100 μg/kg\nKidney\n50 μg/kg\nMilk\nPorcine\n50 μg/kg\nMuscle\n400 μg/kg\nLiver\n100 μg/kg\nKidney’\n5.. Corticoides\n5.1. Glucocorticoides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Dexamethasone\nDexamethasone\nBovine\n03 μg/kg\nMilk\nBovine, porcine, equidae\n0,75 μg/kg\nMuscle\n2 μg/kg\nLiver\n0,75 μg/kg\nKidney’\nB.. Annexe II to Regulation (EEC) No 2377/90 is amended as follows:\n1.. Inorganic chemicals\nPharmacologically active substance(s)\nAnimal species\nOther provisions\n‘Bismuth subcarbonate\nAll food producing species\nFor oral use only\nBismuth subgallate\nAll food producing species\nFor oral use only\nBismuth subnitrate\nAll food producing species\nFor oral use only\nBismuth subsalicylate\nAll food producing species\nFor oral use only\nBoric acid and borates\nAll food producing species\nBromide, Sodium salt\nAll mammalian food producing species\nFor topical use only\nCalcium acetate\nAll food producing species\nCalcium benzoate\nCalcium carbonate\nCalcium chloride\nCalcium gluconate\nCalcium hydroxide\nCalcium hypophosphite\nCalcium malate\nCalcium oxide\nCalcium phosphate\nCalcium polyphosphates\nCalcium propionate\nCalcium silicate\nCalcium stearate\nCalcium sulphate\nHydrochloric acid\nAll food producing species\nFor use as excipient\nHydrogen peroxide\nAll food producing species\nIodine and iodine inorganic compounds including:\nAll food producing species\nSodium and potassium-iodide\nSodium and potassium-iodide\nIodophors including polyvinylpyrrolidone-iodine\nMagnesium\nAll food producing species\nMagnesium sulphate\nMagnesium hydroxide\nMagnesium stearate\nMagnesium glutamate\nMagnesium orotate\nMagnesium aluminium silicate\nMagnesium oxide\nMagnesium carbonate\nMagnesium phosphate\nMagnesium glycerophosphate\nMagnesium asparate\nMagnesium citrate\nMagnesium acetate\nMagnesium trisilicate\nPotassium DL-aspartate\nAll food producing species\nPotassium glucuronate\nAll food producing species\nPotassium glycerophosphate\nAll food producing species\nPotassium nitrate\nAll food producing species\nPotassium selenate\nAll food producing species\nSodium chlorite\nBovine\nFor topical use only\nSodium dichloroisocyanurate\nBovine, ovine, caprine\nFor topical use only’\nSodium selenate\nAll food producing species\nSodium selenite\nAll food producing species\nSulphur\nBovine, porcine, ovine, caprine, equidae\nZinc acetate\nAll food producing species\nZinc chloride\nZinc gluconate\nZinc oleate\nZinc stearate\n2.. Organic compounds\nPharmacologically active substance(s)\nAnimal species\nOther provisions\n‘17B-Oestradiol\nAll mammalian food producing species\nFor therapeutic and zootechnical uses only\nAcetyl cysteine\nAll food producing species\nAlfaprostol\nBovine, porcine, equidae\nBenzylalcohol\nAll food producing species\nFor use as excipient\nBetaine\nAll food producing species\nBrotizolam\nBovine\nFor therapeutic uses only\nBuserelin\nAll food producing species\nButyl 4-hydroxybenzoate\nAll food producing species\nCaffeine\nAll food producing species\nCarbetocin\nAll mammalian food producing species\nCefazolin\nBovine\nOvine, caprine\nFor intramammary use (except if the udder may be used as food for human consumption)\nCetrimide\nAll food producing species\nChlorhexidine\nAll food producing species\nFor topical use only\nChlorocresol\nAll food producing species\nCloprostenol\nBovine, porcine, equidae\nD-phe 6-luteinizing-hormone-releasing-hormone\nAll food producing species\nDembrexine\nEquidae\nDetomidine\nBovine, equidae\nFor therapeutic uses only\nDiclazuril\nOvine\nFor oral use in lambs only\nDicloxacillin\nAll food producing species\nDiethyl phtalate\nAll food producing species\nDimethyl phtalate\nAll food producing species\nDinoprost tromethamine\nAll mammalian food producing species\nEtamiphylline camsylate\nAll food producing species\nEthanol\nAll food producing species\nFor use as excipient\nEthyl lactate\nAll food producing species\nEtiproston tromethamine\nBovine, porcine\nFertirelin acetate\nBovine\nFolic acid\nAll food producing species\nGlycerol formal\nAll food producing species\nGonadotrophin releasing hormone\nAll food producing species\nHeptaminol\nAll food producing species\nHesperidin\nEquidae\nHesperidin methyl chalcone\nEquidae\nHuman chorion gonadotrophin (HCG)\nAll food producing species\nHuman menopausal urinary gonadotrophin\nBovine\nIodine organic compounds:\nIodoform\nAll food producing species\nIsobutane\nAll food producing species\nIsoflurane\nEquidae\nFor use as anaesthetic only\nIsoxsuprine\nBovine, equidae\nFor therapeutic use only in accordance with Council Directive 96/22/EEC (OJ L 125, 23.5.1996, p. 3)\nKetanserin tartrate\nEquidae\nKetoprofen\nBovine, equidae\nPorcine\nL-tartaric acid and its mono- and di- basic salt of sodium, potassium and calcium\nAll food producing species\nFor use as excipient\nLactic acid\nAll food producing species\nLecirelin\nLini oleum\nAll food producing species\nLobeline\nAll food producing species\nLuprostiol\nAll mammalian species\nMalic acid\nAll food producing species\nFor use as excipient\nMedroxyprogesterone acetate\nOvine\nFor intravaginal use for zootechnical purposes only\nMelatonin\nOvine, caprine\nMenbutone\nBovine, ovine, caprine, porcine, equidae\nMenthol\nAll food producing species\nMineral hydrocarbons, low to high viscosity including micro-cristalline waxes, approximately C10-C60; aliphatic, branched aliphatic and alicyclic compounds\nAll food producing species\nExcludes aromatic and unsaturated compounds\nN-butane\nAll food producing species\nN-butanol\nAll food producing species\nFor use as excipient\nNeostigmine\nAll food producing species\nOxytocin\nAll mammalian food producing species\nPancreatin\nAll mammalian food producing species\nFor topical use only\nPapain\nAll food producing species\nPapaverine\nBovine\nNew-born calves only\nPeracetic acid\nAll food producing species\nPhenol\nAll food producing species\nPhloroglucinol\nAll food producing species\nPolicresulene\nAll food producing species\nFor topical use only\nPolysulphated glycosaminoglycan\nEquidae\nPraziquantel\nOvine\nFor non-lactating sheep only\nPregnant mare serum gonadotrophin\nAll food producing species\nPropane\nAll food producing species\nPropylene glycol\nAll food producing species\nQuatresin\nAll food producing species\nFor use as preservative only at concentrations of up to 0,5 %\nQuillaia saponins\nAll food producing species\nR-clopostenol\nBovine, porcine, equidae\nRifaximin\nBovine\nFor intramammary use - except if the udder may be used as food for human consumption - and intra-uterine use only\nRomifidine\nEquidae\nFor therapeutic uses only\nSodium benzyl 4-hydroxybenzoate\nAll food producing species\nSodium butyl 4-hydroxybenzoate\nAll food producing species\nSomatosalm\nSalmon\nTau fluvalinate\nHoney bees\nTheobromine\nAll food producing species\nTheophylline\nAll food producing species\nThiomersal\nAll food producing species\nFor use only as preservatives in multi-dose vaccines at a concentration not exceeding 0,02 %\nThymol\nAll food producing species\nTimerfonate\nAll food producing species\nFor use only as preservatives in multi-dose vaccines at a concentration not exceeding 0,02 %’\nTrimethylphloroglucinol\nAll food producing species\n3.. Substances generally recognised as safe\nPharmacologically active substance(s)\nAnimal species\nOther provisions\n‘Absinthium extract\nAll food producing species\nAcetylmethionine\nAll food producing species\nAluminium hydroxide\nAll food producing species\nAluminium monostearate\nAll food producing species\nAmmonium sulfate\nAll food producing species\nBenzoyl benzoate\nAll food producing species\nBenzyl p-hydroxybenzoate\nAll food producing species\nCalcium borogluconate\nAll food producing species\nCalcium citrate\nAll food producing species\nCamphor\nAll food producing species\nExternal use only’\nCardamon extract\nAll food producing species\nDiethyl sebacate\nAll food producing species\nDimethicone\nAll food producing species\nDimethyl acetamide\nAll food producing species\nDimethyl sulphoxide\nAll food producing species\nEpinephrine\nAll food producing species\nEthyl oleate\nAll food producing species\nEthylenediaminetetraacetic acid and salts\nAll food producing species\nEucalyptol\nAll food producing species\nFollicle stimulating hormone (natural FSH from all species and their synthetic analogues)\nAll food producing species\nFormaldehyde\nAll food producing species\nFormic acid\nAll food producing species\nGlutaraldehyde\nAll food producing species\nGuaiacol\nAll food producing species\nHeparin and its salts\nAll food producing species\nHuman chorionic gonadotropin (natural HCG and its synthetic analogues)\nAll food producing species\nIron ammonium citrate\nAll food producing species\nIron dextran\nAll food producing species\nIron glucoheptonate\nAll food producing species\nIsopropanol\nAll food producing species\nLuteinising hormone (natural LH from all species and their synthetic analogues)\nAll food producing species\nLanolin\nAll food producing species\nMagnesium chloride\nAll food producing species\nMagnesium gluconate\nAll food producing species\nMagnesium hypophosphite\nAll food producing species\nMannitol\nAll food producing species\nMethylbenzoate\nAll food producing species\nMonothioglycerol\nAll food producing species\nMontanide\nAll food producing species\nMyglyol\nAll food producing species\nOrgotein\nAll food producing species\nPoloxalene\nAll food producing species\nPoloxamer\nAll food producing species\nPolyethylene glycols (molecular weight ranging from 200 to 10 000)\nAll food producing species\nPolysorbate 80\nAll food producing species\nSerotonin\nAll food producing species\nSodium chloride\nAll food producing species\nSodium cromoglycate\nAll food producing species\nSodium dioctylsulphosuccinate\nAll food producing species\nSodium formaldehydesulphoxylate\nAll food producing species\nSodium lauryl sulphate\nAll food producing species\nSodium pyrosulphite\nAll food producing species\nSodium stearate\nAll food producing species\nSodium thiosulphate\nAll food producing species\nTragacanth\nAll food producing species\nUrea\nAll food producing species\nZinc oxide\nAll food producing species\nZinc sulphate\nAll food producing species\n4.. Substances used in homeopathic veterinary medicinal products\nPharmacologically active substance(s)\nAnimal species\nOther provisions\n‘All substances used in homeopathic veterinary medicinal products provided that their concentration in the product does not exceed one part per 10 000\nAll food producing species’\n5.. Substances used as food additives in foodstuffs for human consumption\nPharmacologically active substance(s)\nAnimal species\nOther provisions\n‘Substances with an E number\nAll food producing species\nOnly substances approved as additives in foodstuffs for human consumption, with the exception of preservatives listed in Part C of Annex III to European Parliament and Council Directive 95/2/EC (OJ L 61, 18. 3. 1995, p. 1.)’\nC.. Annex III to Regulation (EEC) No 2377/90 is amended as follows:\n1.. Anti-infectious agents\n1.1. Chemotherapeutics\n1.1.2. Benzenesulphonamides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Clorsulon\nClorsulon\nBovine\n50 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 2000’\n150 μg/kg\nLiver\n400 μg/kg\nKidney\n1.2. Antibiotics\n1.2.1. Beta-lactamase inhibitors\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Clavulanic acid\nClavulanic acid\nBovine, ovine\n200 μg/kg\nMilk\nProvisional MRLs expire on 1 July 1999’\nBovine, ovine, porcine\n200 μg/kg\nMuscle\n200 μg/kg\nFat\n200 μg/kg\nLiver\n200 μg/kg\nKidney\n1.2.2. Macrolides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Erythromycin\nErythromycin\nBovine, ovine\n40 μg/kg\nMilk\nProvisional MRLs expire on 1 June 2000; MRLs apply to all microbiological active residues expressed as erythromycin equivalent\nBovine, ovine, porcine, poultry\n400 μg/kg\nMuscle\n400 μg/kg\nFat\n400 μg/kg\nLiver\n400 μg/kg\nKidney\nPoultry\n200 μg/kg\nEggs\nJosamycin\nJosamycin\nChicken\n200 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 2000’\n200 μg/kg\nFat\n200 μg/kg\nLiver\n400 μg/kg\nKidney\n200 μg/kg\nEggs\n1.2.4. Cephalosporins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Ceftiofur\nSum of all residues retaining the betalactam structure expressed as desfuroylceftiofur\nBovine\n200 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 1999\n600 μg/kg\nFat\n2 000 μg/kg\nLiver\n2 000 μg/kg\nKidney\n100 μg/kg\nMilk\nPorcine\n500 μg/kg\nMuscle\n600 μg/kg\nFat\n3 000 μg/kg\nLiver\n4 000 μg/kg\nKidney\nCephapirin\nSum of cephapirin and desacetylcephapirin\nBovine\n50 μg/kg\n50 μg/kg\nMuscle\nFat\nProvisional MRLs expire on 1 January 1999’\n50 μg/kg\nLiver\n100 μg/kg\nKidney\n10 μg/kg\nMilk\n1.2.5. Aminoglycosides\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Aminosidine\nAminosidine\nBovine, porcine, rabbits, chicken\n500 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 2000\n1 500 μg/kg\nLiver\n1 500 μg/kg\nkidney\nApramycin\nApramycin\nBovine (for use in non-lactating cattle only)\n1 000 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 1999\n1 000 μg/kg\nLiver\n10 000 μg/kg\nLiver\n20 000 μg/kg\nKidney\nPorcine\n1 000 μg/kg\nMuscle\n1 000 μg/kg\nSkin and fat\n1 000 μg/kg\nLiver\n5 000 μg/kg\nKidney\nDihydrostreptomycin\nDihydrostreptomycin\nBovine, ovine\n200 μg/kg\nMilk\nProvisional MRLs expire on 1 June 2000\nBovine, ovine, porcine, poultry\n500 μg/kg\nMuscle\n500 μg/kg\nFat\n500 μg/kg\nLiver\n1 000 μg/kg\nKidney\nGentamicin\nGentamicin\nBovine\n100 μg/kg\nMilk\nProvisional MRLs expire on 1 June 2000\nBovine, porcine\n100 μg/kg\nMuscle\n100 μg/kg\nFat\n200 μg/kg\nLiver\n1 000 μg/kg\nKidney\nNeomycin (including\nNeomycin\nBovine, ovine, caprine\n500 μg/kg\nMilk\nProvisional MRLs expire on 1 June 2000 framycetin)\nBovine, ovine, caprine, porcine, chicken,\n500 μg/kg\nMuscle turkey, duck\n500 μg/kg\nFat\n500 μg/kg\nLiver\n5 000 μg/kg\nKidney\nChicken\n500 μg/kg\nEggs\nSpectinomycin\nSpectinomycin\nBovine\n200 μg/kg\nMilk\nProvisional MRLs expire on 1 July 1998\nBovine, porcine, poultry\n300 μg/kg\nMuscle\n500 μg/kg\nFat\n2 000 μg/kg\nLiver\n5 000 μg/kg\nKidney\nStreptomycin\nStreptomycin\nBovine, ovine\n200 μg/kg\nMilk\nProvisional MRLs expire on 1 June 2000’\nBovine, ovine, porcine, poultry\n500 μg/kg\nMuscle\n500 μg/kg\nFat\n500 μg/kg\nLiver\n1 000 μg/kg\nKidney\n1.2.6. Quinolones\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Decoquinate\nDecoquinate\nBovine, ovine\n500 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 2000\n500 μg/kg\nFat\n500 μg/kg\nLiver\n500 μg/kg\nKidney\nFlumequine\nFlumequine\nBovine, ovine, porcine, chicken\n50 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 2000\nFlumequine\nFlumequine\nBovine, ovine, porcine, chicken\n50 μg/kg\nFat or skin + fat\nProvisional MRLs expire on 1 January 2000\n100 μg/kg\nLiver\n300 μg/kg\nKidney\nSalmonidae\n150 μg/kg\nMarbofloxacin\nMarbofloxacin\nBovine\n150 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 2000\n50 μg/kg\nFat\n150 μg/kg\nLiver\n150 μg/kg\nKidney\n75 μg/kg\nMilk\nPorcine\n150 μg/kg\nMuscle\n50 μg/kg\nSkin + fat\n150 μg/kg\nLiver\n150 μg/kg\nKidney\nSarafloxacin\nSarafloxacin\nSalmonidae\n30 μg/kg\nMuscle and skin in natural proportions\nProvisional MRLs expire on 1 July 1998’\n1.2.9. Polymyxins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Colistin\nColistin\nBovine, ovine\n50 μg/kg\nMilk\nProvisional MRLs expire on 1 July 2000’\nBovine, ovine, porcine, chicken, rabbits\n150 μg/kg\nMuscle\n150 μg/kg\nFat\n150 μg/kg\nLiver\n200 μg/kg\nKidney\nChicken\n300 μg/kg\nEggs\n1.2.10. Penicillins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Nafcillin\nNafcillin\nBovine\n30 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 1999\nFor intramammary use only\n30 μg/kg\nFat\n30 μg/kg\nLiver\n30 μg/kg\nKidney\n30 μg/kg\nMilk\nPenethamate\nBenzylpenicillin\nOvine\n150 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 2000’\n150 μg/kg\nFat\n150 μg/kg\nLiver\n150 μg/kg\nKidney\n4 μg/kg\nMilk\nPorcine\n50 μg/kg\nMuscle\n50 μg/kg\nFat\n50 μg/kg\nLiver\n50 μg/kg\nKidney\n1.2.11. Florfenicol and related compounds\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Florfenicol\nSum of florfenicol and its metabolites measured as florfenicol-amine\nFish\n1 000 μg/kg\nMuscle and skin in natural proportions\nProvisional MRLs expire on 1 July 2001’\n2.. Antiparasitic agents\n2.1. Agents acting against endoparasites\n2.1.2. Benzimidazoles and pro-benzimidazoles\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Albendazole sulphoxide\nSum of albendazole, albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole\nBovine, ovine\n100 μg/kg\nMilk\nProvisional MRLs expire on 1 January 2000\nBovine, ovine, pheasant\n100 μg/kg\nMuscle\n100 μg/kg\nFat\n1 000 μg/kg\nLiver\n500 μg/kg\nKidney\nNetobimin\nSum of netobimin and albendazole and metabolites of albendazole measured as 2-amino-benzimidazole sulphone\nBovine, ovine, caprine\n100 μg/kg\nMuscle\nProvisional MRLs expire on 31 July 1999’\n100 μg/kg\nFat\n1 000 μg/kg\nLiver\n500 μg/kg\nKidney\n100 μg/kg\nMilk\n2.2. Agents acting against ectoparasites\n2.2.1. Formamidines\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Amitraz\nSum of amitraz and metabolites which are measured as 2,4-dime-thylaniline\nBovine\n200 μg/kg\nFat\nProvisional MRLs expire on 1 July 1998\n200 μg/kg\nLiver\n200 μg/kg\nKidney\n10 μg/kg\nMilk\nOvine\n400 μg/kg\nFat\n200 μg/kg\nLiver\n200 μg/kg\nKidney\nSum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz\nBees\n200 μg/kg\nHoney\nProvisional MRLs expire on 1 July 1999’\n2.2.2. Iminophenyl thiazolidine derivative\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Cymiazole\nCymiazole\nBees\n1 000 μg/kg\nHoney\nProvisional MRLs expire on 1 July 1999’\n2.2.4. Organophosphates\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Azamethiphos\nAzamethiphos\nSalmonidae\n100 μg/kg\nMuscle and skin in natural proportions\nProvisional MRLs expire on 1 June 1999’\n2.2.5. Acyl urea derivates\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Teflubenzuron\nTeflubenzuron\nSalmonidae\n500 μg/kg\nMuscle And skin in natural proportions\nProvisional MRLs expire on 1 July 1999’\n2.3. Agents acting against endo- and ectoparasites\n2.3.1. Avermectins\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Ivermectin\n22,23-Dihydro-aver-mectin Bla\nDeer, including reindeer\n20 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 1999\n100 μg/kg\nFat\n50 μg/kg\nLiver\n20 μg/kg\nKidney\nMoxidectin\nMoxidectin\nEquidae\n50 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 2000’\n500 μg/kg\nFat\n100 μg/kg\nLiver\n50 μg/kg\nKidney\n3.. Agents acting on the nervous system\n3.2. Agents acting on the autonomic nervous system\n3.2.1. 62 sympathomimetic agents\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Clenbuterol hydrochloride\nClenbuterol\nBovine (indication: solely for tocolysis in parturient cows)\n0,1 μg/kg\nMuscle\nProvisional MRLs expire on 1 July 2000’\n0,5 μg/kg\nLiver\n0,5 μg/kg\nKidney\n0,05 μg/kg\nMilk\nEquidae (indications: locolysis and the treatment of respiratory ailments)\n0,1 μg/kg\nMuscle\n0,5 μg/kg\nLiver\n0,5 μg/kg\nKidney\n5.. Anti-inflammatory agents\n5.1. Non-steroidal anti-inflammatory agents\n5.1.1. Arylpropionic acid derivative\nPharmacologically active substance(s)\nMarker residue\nAnimal species\nMRLs\nTarget tissues\nOther provisions\n‘Carprofen\nCarprofen\nBovine\n500 μg/kg\nMuscle\nProvisional MRLs expire on 1 January 2000’\n500 μg/kg\nFat\n1 000 μg/kg\nLiver\n1 000 μg/kg\nKidney\nEquidae\n50 μg/kg\nMuscle\n100 μg/kg\nFat\n1 000 μg/kg\nLiver\n1 000 μg/kg\nKidney\nD.. Annex IV to Regulation (EEC) No 2377/90 is amended as follows:\nPharmacologically active substance(s)\n‘Chloramphenicol\nChloroform\nChlorpromazine\nColchicine\nDapsone\nDimetridazole\nFurazolidone\nMetronidazole\nNitrofurans\nRonidazole’",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/1998/1570/annex",
    "retrieved_at": "2026-11-01T14:58:15.154424+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}