{
  "url": "https://openlegislation.uk/eu-regulation-2001-2380/annex",
  "json_url": "https://openlegislation.uk/eu-regulation-2001-2380/annex.json",
  "legislation": "eur/2001/2380",
  "legislation_title": "Commission Regulation (EC) No 2380/2001 of 5 December 2001 concerning the 10 year authorisation of an additive in feedingstuffs (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2001-2380",
  "path": "annex",
  "kind": "annex",
  "number": null,
  "heading": null,
  "text": "Identification number of the additive\nName of the holder of authorisation\nAdditive (Trade name)\nComposition, chemical formula, description, analytical method\nSpecies or category of animal\nMaximum age\nMinimum content\nMaximum content\nOther provisions\nEnd of period of authorisation\nmg of active substance/kg of complete feedingstuff with a moisture content of 12 %\nCoccidiostats and other medicinal substances\nE 770\nZoetis Belgium SA\nMaduramicin ammonium\nalpha 1 g/100 g\n(Cygro 1 %)\nAdditive composition\nMaduramicin ammonium alpha: 1 g/100 g\nCarboxymethylcellulose sodium: 2 g/100 g\nCalcium sulphate dihydrate: 97 g/100 g\nActive substance\nMaduramicin ammonium α C 47 H 83 O 17 N\nCAS number: 84878-61-5, ammonium salt of a polyether monocarboxylic acid produced by a fermentation process by the strain Actinomadura yumaensis (ATCC 31585) (NRRL 12515)\nRelated impurities:\nMaduramicin ammonium β: < 10 %\nTurkeys\n16 weeks\n5\n5\n1.\nUse prohibited at least 5 days before slaughter.\n2.\nIndicate in the instructions for use: ‘Dangerous for equines’.\n‘ This feedingstuff contains an ionophore: simultaneous use with certain medicinal substances (e.g. tiamulin) can be contraindicated ’ .\n15.12.2011",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Substituted by Commission Implementing Regulation (EU) No 406/2011 of 27 April 2011 amending Regulation (EC) No 2380/2001 as regards the composition of the feed additive maduramicin ammonium alpha (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F2",
      "text": "Substituted by Commission Implementing Regulation (EU) No 1014/2013 of 22 October 2013 amending Regulations (EC) No 2380/2001, (EC) No 1289/2004, (EC) No 1455/2004, (EC) No 1800/2004, (EC) No 600/2005, (EU) No 874/2010, Implementing Regulations (EU) No 388/2011, (EU) No 532/2011 and (EU) No 900/2011 as regards the name of the holder of the authorisation of certain additives in animal feed (Text with EEA relevance)."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2001/2380/annex",
    "retrieved_at": "2026-11-01T14:56:42.682865+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}