# Regulation (EC) No 999/2001 of the European Parliament and of the Council of 22 May 2001 laying down rules for the prevention, control and eradication of certain transmissible spongiform encephalopathies, Division 3.3: Laboratory testing for the presence of TSEs in species other than those referred to in points 3.1 and 3.2

Extent: E+W+S+N.I.

Where methods and protocols are established for tests carried out to confirm the suspected presence of a TSE in a species other than bovine, ovine and caprine, they shall include at least a histopathological examination of brain tissue. The competent authority may also require laboratory tests such as immunohistochemistry, Western blotting, demonstration of characteristic fibrils by electron microscopy or other methods designed to detect the disease associated form of the prion protein. In any case at least one other laboratory examination shall be carried out if the initial histopathological examination is negative or inconclusive. At least three different examinations with positive results shall be carried out in the event of the first appearance of the disease.
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Source: https://www.legislation.gov.uk/eur/2001/999/annex/X/chapter/C/division/3/division/3.3 (the official version)
Page: https://openlegislation.uk/eu-regulation-2001-999/annex-X/chapter-C/division-3/division-3.3
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.