# Regulation (EC) No 853/2004 of the European Parliament and of the Council of 29 April 2004 laying down specific hygiene rules for food of animal origin, Division 1: The production process for collagen must ensure that:

Extent: E+W+S+N.I.

(a) all ruminant bone material derived from animals born, reared or slaughtered in countries or regions with a controlled or undetermined BSE risk as determined in accordance with Article 5 of Regulation (EC) No 999/2001 is subjected to a process which ensures that all bone material is finely crushed and degreased with hot water and treated with dilute hydrochloric acid (at a minimum concentration of 4 % and pH < 1,5) over a period of at least 2 days; this treatment must be followed by pH adjustment using acid or alkali followed by:
(i) either one or more rinses and at least one of the following processes:
filtration,
milling,
extrusion,
(ii) or any approved equivalent process;
(b) raw materials other than that referred to in point (a) must be subjected to a treatment involving washing, pH adjustment using acid or alkali followed by:
(i) either one or more rinses and at least one of the following processes:
filtration,
milling,
extrusion,
(ii) or any approved equivalent process.

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Source: https://www.legislation.gov.uk/eur/2004/853/annex/III/section/XV/chapter/III/division/1 (the official version)
Page: https://openlegislation.uk/eu-regulation-2004-853/annex-III/section-XV/chapter-III/division-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.