{
  "url": "https://openlegislation.uk/eu-regulation-2005-943/annex-II",
  "json_url": "https://openlegislation.uk/eu-regulation-2005-943/annex-II.json",
  "legislation": "eur/2005/943",
  "legislation_title": "Commission Regulation (EC) No 943/2005 of 21 June 2005 concerning the permanent authorisation of additives in feedingstuffs (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2005-943",
  "path": "annex/II",
  "kind": "annex",
  "number": "II",
  "heading": null,
  "text": "1 U is the amount of enzyme which liberates 5,55 micromoles of reducing sugars (maltose equivalents) from barley beta-glucan per minute at pH 5,0 and 50 °C.\n1 U is the amount of enzyme which liberates 4,00 micromoles of reducing sugars (maltose equivalents) from birchwood xylan per minute at pH 5,5 and 50 °C.\n1 IFP is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 4,8 and 50 °C.\nEC No\nAdditive\nChemical formula, description\nSpecies or category of animal\nMaximum age\nMinimum content\nMaximum content\nOther provisions\nEnd of period of authorisation\nUnits of activity/kg of complete feedingstuff\nEnzymes\nE 1604\nEndo-1,3(4)-beta-glucanase\nEC 3.2.1.6\nEndo-1,4-beta-xylanase\nEC 3.2.1.8\nPreparation of endo-1,3(4)-beta-glucanase and endo-1,4-beta-xylanase produced by Penicillium funiculosum (IMI SD 101) having a minimum activity of:\nPowder form:\nendo-1,3(4)-beta-glucanase: 2 000 U/g\nendo-1,4-beta-xylanase: 1 400 U/g\nLiquid form:\nendo-1,3(4)-beta-glucanase: 500 U/ml\nendo-1,4-beta-xylanase: 350 U/ml\nLaying hens\n—\nEndo-1,3(4)-beta-glucanase: 100 U\n—\n1.\nIn the directions for use of the additive and premixture, indicate the storage temperature, storage life, and stability to pelleting.\n2.\nRecommended dose per kg of complete feedingstuff:\nendo-1,3(4)-beta-glucanase: 100 U\nendo-1,4-beta-xylanase: 70 U\n3.\nFor use in compound feed rich in non-starch polysaccharides, (mainly beta-glucans and arabinoxylans), e.g. containing more than 60 % barley or 30 % wheat.\nWithout a time-limit\nEndo-1,4-beta-xylanase: 70 U\n—\nTurkeys for fattening\n—\nEndo-1,3(4)-beta-glucanase: 100 U\n—\n1.\nIn the directions for use of the additive and premixture, indicate the storage temperature, storage life, and stability to pelleting.\n2.\nRecommended dose per kg of complete feedingstuff:\nendo-1,3(4)-beta-glucanase: 100 U\nendo-1,4-beta-xylanase: 70 U\n3.\nFor use in compound feed rich in non-starch polysaccharides, (mainly beta-glucans and arabinoxylans), e.g. containing more than 30 % barley or 20 % wheat.\nWithout a time-limit\nEndo-1,4-beta-xylanase: 70 U\n—\nE 1613\nEndo-1,4-beta-xylanase\nEC 3.2.1.8\nPreparation of endo-1,4-beta-xylanase produced by Trichoderma longibrachiatum (CNCM MA 6-10 W) having a minimum activity of:\nPowder form: 70 000 IFP/g\nPowder form: 7 000 IFP/ml\nTurkeys for fattening\n—\n1 400 IFP\n—\n1.\nIn the directions for use of the additive and premixture, indicate the storage temperature, storage life and stability to pelleting.\n2.\nRecommended dose per kg of complete feedingstuff: 1 400 IFP\n3.\nFor use in compound feed rich in non- starch polysaccharides (mainly arabinoxylans), e.g. containing more than 38 % wheat.\nWithout a time-limit",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Deleted by Commission Implementing Regulation (EU) 2017/1145 of 8 June 2017 on the withdrawal from the market of certain feed additives authorised pursuant to Council Directives 70/524/EEC and 82/471/EEC and repealing the obsolete provisions authorising those feed additives (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F2",
      "text": "Deleted by Commission Implementing Regulation (EU) No 290/2014 of 21 March 2014 concerning the authorisation of a preparation of endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase produced by Talaromyces versatilis sp. nov. IMI CC 378536 as a feed additive for poultry, weaned piglets and pigs for fattening and amending Regulations (EC) No 1259/2004, (EC) No 943/2005, (EC) No 1206/2005 and (EC) No 322/2009 (holder of the authorisation Adisseo France S.A.S.) (Text with EEA relevance)."
    },
    {
      "type": "footnote",
      "label": "f1",
      "text": "1 U is the amount of enzyme which liberates 5,55 micromoles of reducing sugars (maltose equivalents) from barley beta-glucan per minute at pH 5,0 and 50 °C."
    },
    {
      "type": "footnote",
      "label": "f2",
      "text": "1 U is the amount of enzyme which liberates 4,00 micromoles of reducing sugars (maltose equivalents) from birchwood xylan per minute at pH 5,5 and 50 °C."
    },
    {
      "type": "footnote",
      "label": "f3",
      "text": "1 IFP is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 4,8 and 50 °C."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2005/943/annex/II",
    "retrieved_at": "2026-11-01T14:54:33.918345+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}