# Commission Regulation (EC) No 401/2006 of 23 February 2006 laying down the methods of sampling and analysis for the official control of the levels of mycotoxins in foodstuffs (Text with EEA relevance), Division 4.3.2.7: Continuous method verification/on-going method validation

Extent: E+W+S+N.I.

After initial validation, additional validation data are acquired by including at least two positive control samples in each batch of samples screened. One positive control sample is a known sample (e.g. one used during initial validation), the other is a different commodity from the same commodity group (in case only one commodity is analysed, a different sample of that commodity is used instead). Inclusion of a negative control sample is optional. The results obtained for the two positive control samples are added to the existing validation set.
At least once a year the cut-off value is re-established and the validity of the method is re-assessed. The continuous method verification serves several purposes:
quality control for the batch of samples screened
providing information on robustness of the method at conditions in the laboratory that applies the method
justification of applicability of the method to different commodities
allowing to adjust cut-off values in case of gradual drifts over time.

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Source: https://www.legislation.gov.uk/eur/2006/401/annex/II/division/4/division/4.3/division/4.3.2/division/4.3.2.7 (the official version)
Page: https://openlegislation.uk/eu-regulation-2006-401/annex-II/division-4/division-4.3/division-4.3.2/division-4.3.2.7
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.