{
  "url": "https://openlegislation.uk/eu-regulation-2006-565/annex",
  "json_url": "https://openlegislation.uk/eu-regulation-2006-565/annex.json",
  "legislation": "eur/2006/565",
  "legislation_title": "Commission Regulation (EC) No 565/2006 of 6 April 2006 imposing testing and information requirements on the importers or manufacturers of certain priority substances in accordance with Council Regulation (EEC) No 793/93 on the evaluation and control of the risks of existing substances (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2006-565",
  "path": "annex",
  "kind": "annex",
  "number": null,
  "heading": null,
  "text": "Substance listed in the Annex to Commission Regulation (EC) No 1179/94 (OJ L 131, 26.5.1994, p. 3; priority list 1).\nSubstance listed in the Annex to Commission Regulation (EC) No 2364/2000 (OJ L 273, 23.10.2000, p. 5; priority list 4).\nSubstance listed in the Annex to Commission Regulation (EC) No 143/97 (OJ L 25, 27.1.1997, p. 13; priority list 3).\nNo\nEinecs No\nCAS No\nSubstance name\nRapporteur\nTesting/Information requirements\nTime limit from the date of entry into force of this Regulation\n1\n214-604-9\n1163-19-5\nBis(pentabromophenyl)ether\nUK/F\nDevelopmental neurotoxicity study in rats or mice\n24 months\nSuitable human bio-monitoring programme, including breast milk and blood, and the need for a trend analysis over a certain period\nAnnual reporting over a period of 10 years\nEnvironmental monitoring programme including birds, sewage sludge, sediment, and air to establish time trends for the substance and its more toxic and bioaccumulative degradation products over a period of ten years\nAnnual reporting over a period of 10 years\n2\n237-158-7\n13674-84-5\nTris(2-chloro-1-methylethyl) phosphate\nUK/IRL\nData on releases and use pattern of certain life cycle stages\n3 months\n3\n237-159-2\n13674-87-8\nTris[2-chloro-1-(chloromethyl) ethyl] phosphate\nUK/IRL\nData on releases and use pattern of certain life cycle stages\n3 months\nSediment-water Chironomid toxicity test using spiked sediment (OECD 218)\n6 months\nSediment-water Lumbriculus toxicity test using spiked sediment\n6 months\nSediment-water Hyallella toxicity test using spiked sediment\n6 months\n4\n253-760-2\n38051-10-4\n2,2-Bis(chloromethyl) trimethylene bis (bis(2-chloroethyl) phosphate\nUK/IRL\nData on releases and use pattern of certain life cycle stages\n3 months\n5\n231-111-4\n232-104-9\n222-068-2\n231-743-0\n236-068-5\n7440-02-0\n7786-81-4\n3333-67-3\n7718-54-9\n13138-45-9\nNickel\nNickel sulphate\nNickel carbonate\nNickel dichloride\nNickel dinitrate\nDK\nInformation on ecotoxicity and bioavailability of nickel in laboratory studies\n3 months\nInformation on ecotoxicity, fate and bioavailability from field studies\n6 months\nInformation on toxicity of nickel in various soil types\n6 months\nDevelopment and validation of a chronic Biotic Ligand Model for Rainbow trout\n3 months\nDevelopment and validation of a chronic Biotic Ligand Model for algae and invertebrates\n3 months\nExposure information for derivation of PEClocal and PECregional\n6 months\nMonitoring data of European surface waters\n6 months\n232-104-9\n7786-81-4\nNickel sulphate\nTwo-year oral carcinogenicity study with nickel sulphate in rats (OECD 451 — B32)\n30 months\n231-111-4\n7440-02-0\nNickel\nTwo-year inhalation carcinogenicity study with elemental nickel metal powder in rat (OECD 451 — B32)\n30 months\n6\n221-221-0\n3033-77-0\n2,3-Epoxypropyltrimethyl ammonium chloride\nFIN\nSimulation test Aerobic sewage treatment, Activated sludge units (OECD 303A)\n6 months\nEnvironmental exposure information\n3 months\n7\n222-048-3\n3327-22-8\n(3-Chloro-2-hydroxypropyl) trimethyl ammonium chloride\nFIN\nSimulation test Aerobic sewage treatment, Activated sludge units (OECD 303A)\n6 months\nEnvironmental exposure information\n3 months\n8\n202-453-1\n95-80-7\n4-Methyl-m-phenylenediamine\nD\nSediment-water Lumbriculus toxicity test using spiked sediment\n6 months",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "footnote",
      "label": "f1",
      "text": "Substance listed in the Annex to Commission Regulation (EC) No 1179/94 (OJ L 131, 26.5.1994, p. 3; priority list 1)."
    },
    {
      "type": "footnote",
      "label": "f2",
      "text": "Substance listed in the Annex to Commission Regulation (EC) No 2364/2000 (OJ L 273, 23.10.2000, p. 5; priority list 4)."
    },
    {
      "type": "footnote",
      "label": "f3",
      "text": "Substance listed in the Annex to Commission Regulation (EC) No 143/97 (OJ L 25, 27.1.1997, p. 13; priority list 3)."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2006/565/annex",
    "retrieved_at": "2026-11-01T14:53:48.196755+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}