Division 3.4.2.2.2.2 F1

Human evidence for sub-category 1B can include:

1. (a)

   positive responses at > 500 μg/cm2 (HRIPT, HMT — induction threshold);

2. (b)

   diagnostic patch test data where there is a relatively low but substantial incidence of reactions in a defined population in relation to relatively high exposure;

3. (c)

   other epidemiological evidence where there is a relatively low but substantial incidence of allergic contact dermatitis in relation to relatively high exposure.

The use of human data is discussed in sections 1.1.1.3, 1.1.1.4 and 1.1.1.5.