{
  "url": "https://openlegislation.uk/eu-regulation-2008-1272/annex-I/division-3/division-3.4/division-3.4.2/division-3.4.2.2/division-3.4.2.2.3/division-3.4.2.2.3.2",
  "json_url": "https://openlegislation.uk/eu-regulation-2008-1272/annex-I/division-3/division-3.4/division-3.4.2/division-3.4.2.2/division-3.4.2.2.3/division-3.4.2.2.3.2.json",
  "legislation": "eur/2008/1272",
  "legislation_title": "Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2008-1272",
  "path": "annex/I/division/3/division/3.4/division/3.4.2/division/3.4.2.2/division/3.4.2.2.3/division/3.4.2.2.3.2",
  "kind": "division",
  "number": "3.4.2.2.3.2",
  "heading": null,
  "text": "Animal test results for sub-category 1A can include data with values indicated in Table 3.4.3\nTable 3.4.3\nAnimal test results for sub-category 1A\nAssay\nCriteria\nLocal lymph node assay\nEC3 value ≤ 2 %\nGuinea pig maximisation test\n≥ 30 % responding at ≤ 0,1 % intradermal induction dose or\n≥ 60 % responding at > 0,1 % to ≤ 1 % intradermal induction dose\nBuehler assay\n≥ 15 % responding at ≤ 0,2 % topical induction dose or\n≥ 60 % responding at > 0,2 % to ≤ 20 % topical induction dose",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Substituted by Commission Regulation (EU) No 286/2011 of 10 March 2011 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2008/1272/annex/I/division/3/division/3.4/division/3.4.2/division/3.4.2.2/division/3.4.2.2.3/division/3.4.2.2.3.2",
    "retrieved_at": "2026-11-01T14:51:47.470832+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}