{
  "url": "https://openlegislation.uk/eu-regulation-2008-1272/annex-IV/division-1",
  "json_url": "https://openlegislation.uk/eu-regulation-2008-1272/annex-IV/division-1.json",
  "legislation": "eur/2008/1272",
  "legislation_title": "Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2008-1272",
  "path": "annex/IV/division/1",
  "kind": "division",
  "number": "1",
  "heading": "Part 1: Criteria for the selection of precautionary statements",
  "text": "Table 6.1\nPrecautionary statements — General\nCode\nGeneral precautionary statements\nHazard class\nHazard category\nConditions for use\n(1)\n(2)\n(3)\n(4)\n(5)\nP101\nIf medical advice is needed, have product container or label at hand.\nas appropriate\nConsumer products\nP102\nKeep out of reach of children.\nas appropriate\nConsumer products\nP103\nRead carefully and follow all instructions.\nas appropriate\nConsumer products – omit where P202 is used\nTable 6.2\nPrecautionary statements — Prevention\nCode\nPrevention precautionary statements\nHazard class\nHazard category\nConditions for use\n(1)\n(2)\n(3)\n(4)\n(5)\nP201\nObtain special instructions before use.\nExplosives (section 2.1)\nUnstable explosive\nGerm cell mutagenicity (section 3.5)\n1A,1B, 2\nConsumer products – omit where P202 is used\nCarcinogenicity (section 3.6)\n1A,1B, 2\nReproductive toxicity (section 3.7)\n1A,1B, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nP202\nDo not handle until all safety precautions have been read and understood.\nFlammable gases (section 2.2)\nA, B (chemically unstable gases)\nGerm cell mutagenicity (section 3.5)\n1A,1B, 2\nCarcinogenicity (section 3.6)\n1A,1B, 2\nReproductive toxicity (section 3.7)\n1A,1B, 2\nReproductive toxicity, effects on or via lactation (section 3.7)\nAdditional category\nP210\nKeep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.\nExplosives (section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.4, 1.5\nFlammable gases (section 2.2)\n1A, 1B, 2\nAerosols (section 2.3)\n1, 2, 3\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nP211\nDo not spray on an open flame or other ignition source.\nAerosols (section 2.3)\n1, 2\nP212\nAvoid heating under confinement or reduction of the desensitising agent.\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nP220\nKeep away from clothing and other combustible materials.\nOxidising gases (Section 2.4)\n1\nOxidising liquids (Section 2.13)\n1, 2, 3\nOxidising solids (Section 2.14)\n1, 2, 3\nP222\nDo not allow contact with air.\nFlammable gases (section 2.2)\nPyrophoric gas\nif emphasis of the hazard statement is deemed necessary .\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nP223\nDo not allow contact with water.\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2\n—\nif emphasis of the hazard statement is deemed necessary\nP230\nKeep wetted with …\nExplosives (section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.5\nManufacturer/supplier to specify appropriate material\nfor substances and mixtures which are wetted, diluted, dissolved or suspended with a phlegmatiser in order to suppress their explosive properties\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nManufacturer/supplier to specify appropriate material\nP231\nHandle and store contents under inert gas/…\nPyrophoric liquids (Section 2.9)\n1\n… Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.\nPyrophoric solids (Section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2, 3\n—\nif the substance or mixture reacts readily with moisture in air.\n… Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.\nP232\nProtect from moisture.\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nP233\nKeep container tightly closed.\nFlammable liquids (section 2.6)\n1, 2, 3\nif the liquid is volatile and may generate an explosive atmosphere\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nif the chemical is volatile and may generate a hazardous atmosphere\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\nP234\nKeep only in original packaging.\nExplosives (Section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.4, 1.5\nSelf-reactive substances and mixtures (Section 2.8)\nTypes A, B, C, D, E, F\nOrganic peroxides (Section 2.15)\nTypes A, B, C, D, E, F\nCorrosive to metals (Section 2.16)\n1\nP235\nKeep cool.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nfor flammable liquids category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere\nSelf-reactive substances and mixtures (Section 2.8)\nTypes A, B, C, D, E, F\n—\nmay be omitted if P411 is given on the label\nSelf-heating substances and mixtures (Section 2.11)\n1, 2\n—\nmay be omitted if P413 is given on the label\nOrganic peroxides (Section 2.15)\nTypes A, B, C, D, E, F\n—\nmay be omitted if P411 is given on the label\nP240\nGround and bond container and receiving equipment.\nExplosives (Section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.4, 1.5\n—\nif the explosive is electrostatically sensitive\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nif the liquid is volatile and may generate an explosive atmosphere\nFlammable solids (Section 2.7)\n1, 2\n—\nif the solid is electrostatically sensitive\nSelf-reactive substances and mixtures (Section 2.8)\nTypes A,B,C, D, E, F\n—\nif electrostatically sensitive and able to generate an explosive atmosphere\nOrganic peroxides (Section 2.15)\nP241\nUse explosion-proof [electrical/ventilating/lighting/…] equipment.\nFlammable liquids (Section 2.6)\n1, 2, 3\nif the liquid is volatile and may generate an explosive atmosphere.\ntext in square brackets may be used to specify specific electrical, ventilating, lighting or other equipment if necessary and as appropriate.\nFlammable solids (Section 2.7)\n1, 2\nif dust clouds can occur.\ntext in square brackets may be used to specify specific electrical, ventilating, lighting or other equipment if necessary and as appropriate.\nP242\nUse non-sparking tools.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nif the liquid is volatile and may generate an explosive atmosphere and if the minimum ignition energy is very low. (This applies to substances and mixtures where the ignition energy is < 0,1 mJ, e.g. carbon disulphide).\nP243\nTake action to prevent static discharges.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nif the liquid is volatile and may generate an explosive atmosphere.\nP244\nKeep valves and fittings free from oil and grease.\nOxidising gases (section 2.4)\n1\nP250\nDo not subject to grinding/shock/friction …\nExplosives (Section 2.1)\nUnstable explosives and divisions 1.1, 1.2, 1.3, 1.4, 1.5\n—\nif the explosive is mechanically sensitive\n… Manufacturer/supplier to specify applicable rough handling.\nP251\nDo not pierce or burn, even after use.\nAerosols (section 2.3)\n1, 2, 3\nP260\nDo not breathe dust/fume/gas/mist/vapours/spray.\nAcute toxicity — inhalation (section 3.1)\n1, 2\nManufacturer/supplier to specify applicable conditions.\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity — repeated exposure (section 3.9)\n1, 2\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSpecify do not breathe dusts or mists.\nif inhalable particles of dusts or mists may occur during use.\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nP261\nAvoid breathing dust/fume/gas/mist/vapours/spray.\nAcute toxicity — inhalation (Section 3.1)\n3, 4\n—\nmay be omitted if P260 is given on the label\nManufacturer/supplier to specify applicable conditions.\nRespiratory sensitisation (Section 3.4)\n1, 1A, 1B\nSkin sensitisation (Section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcotic effects (Section 3.8)\n3\nP262\nDo not get in eyes, on skin, or on clothing.\nAcute toxicity — dermal (section 3.1)\n1, 2\nP263\nAvoid contact during pregnancy and while nursing.\nReproductive toxicity — effects on or via lactation (Section 3.7)\nAdditional category\nP264\nWash … thoroughly after handling.\nAcute toxicity — oral (section 3.1)\n1, 2, 3, 4\nManufacturer/supplier to specify parts of the body to be washed after handling.\nAcute toxicity — dermal (section 3.1)\n1, 2\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSkin irritation (section 3.2)\n2\nEye irritation (section 3.3)\n2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity — repeated exposure (section 3.9)\n1\nP270\nDo not eat, drink or smoke when using this product.\nAcute toxicity — oral (section 3.1)\n1, 2, 3, 4\nAcute toxicity — dermal (section 3.1)\n1, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity — repeated exposure (section 3.9)\n1\nP271\nUse only outdoors or in a well-ventilated area.\nAcute toxicity — inhalation (section 3.1)\n1, 2, 3, 4\nSpecific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (section 3.8)\n3\nP272\nContaminated work clothing should not be allowed out of the workplace.\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP273\nAvoid release to the environment.\nHazardous to the aquatic environment — acute aquatic hazard (section 4.1)\n1\nif this is not the intended use.\nHazardous to the aquatic environment — long-term aquatic hazard (section 4.1)\n1, 2, 3, 4\nP280\nWear protective gloves/protective clothing/eye protection/face protection/hearing protection/…\nExplosives (section 2.1)\nUnstable explosive and divisions 1.1, 1.2, 1.3, 1.4, 1.5\nManufacturer/supplier to specify the appropriate type of personal protective equipment.\nFlammable gases (section 2.2)\nPyrophoric gas\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSelf-heating substances and mixtures (section 2.11)\n1, 2\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidizing liquids (section 2.13)\n1, 2, 3\nOxidizing solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nSpecify protective gloves/clothing.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSpecify protective gloves/clothing and eye/face protection.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin irritation (section 3.2)\n2\nSpecify protective gloves.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nSerious eye damage (section 3.3)\n1\nSpecify eye/face protection.\nManufacturer/supplier may further specify type of equipment where appropriate.\nEye irritation (section 3.3)\n2\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nManufacturer/supplier to specify the appropriate type of personal protective equipment.\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nP282\nWear cold insulating gloves and either face shield or eye protection.\nGases under pressure (Section 2.5)\nRefrigerated liquefied gas\nP283\nWear fire resistant or flame retardant clothing.\nOxidising liquids (Section 2.13)\n1\nOxidising solids (Section 2.14)\n1\nP284\n[In case of inadequate ventilation] wear respiratory protection.\nAcute toxicity — inhalation (Section 3.1)\n1, 2\n—\ntext in square brackets may be used if additional information is provided with the chemical at the point of use that explains what type of ventilation would be adequate for safe use.\nManufacturer/supplier to specify equipment.\nRespiratory sensitisation (Section 3.4)\n1, 1A, 1B\nP231 + P232\nHandle and store contents under inert gas/…\nProtect from moisture.\nPyrophoric liquids (Section 2.9)\n1\n… Manufacturer/supplier to specify the appropriate liquid or gas if ‘ inert gas ’ is not appropriate.\nPyrophoric solids (Section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2, 3\n—\nif the substance or mixture reacts readily with moisture in air.\n… Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.\nTable 6.3\nPrecautionary statements — Response\nCode\nResponse precautionary statements\nHazard class\nHazard category\nConditions for use\n(1)\n(2)\n(3)\n(4)\n(5)\nP301\nIF SWALLOWED:\nAcute toxicity – oral (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1, 1A, 1B, 1C\nAspiration Hazard (section 3.10)\n1\nP302\nIF ON SKIN:\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP303\nIF ON SKIN (or hair):\nFlammable liquids (section 2.6)\n1, 2, 3\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nP304\nIF INHALED:\nAcute toxicity — inhalation (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (section 3.8)\n3\nP305\nIF IN EYES:\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSerious eye damage/eye irritation (section 3.3)\n1\nEye irritation (section 3.3)\n2\nP306\nIF ON CLOTHING:\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nP308\nIF exposed or concerned:\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nSpecific target organ toxicity, single exposure (section 3.8)\n1, 2\nP310\nImmediately call a POISON CENTER/doctor/…\nAcute toxicity — oral (section 3.1)\n1, 2, 3\n…Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nAcute toxicity — dermal (section 3.1)\n1, 2\nAcute toxicity — inhalation (section 3.1)\n1, 2\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSerious eye damage/eye irritation (section 3.3)\n1\nAspiration hazard (section 3.10)\n1\nP311\nCall a POISON CENTER/doctor/…\nAcute toxicity — inhalation (section 3.1)\n3\n…Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\nP312\nCall a POISON CENTRE/doctor/… if you feel unwell.\nAcute toxicity — oral (Section 3.1)\n4\n… Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nAcute toxicity — dermal (Section 3.1)\n3, 4\nAcute toxicity — inhalation (Section 3.1)\n4\nSpecific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcotic effects (Section 3.8)\n3\nP313\nGet medical advice/attention.\nSkin irritation (section 3.2)\n2, 3\nEye irritation (section 3.3)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nP314\nGet medical advice/attention if you feel unwell.\nSpecific target organ toxicity — repeated exposure (section 3.9)\n1, 2\nP315\nGet immediate medical advice/attention.\nGases under pressure (section 2.5)\nRefrigerated liquefied gas\nP320\nSpecific treatment is urgent (see … on this label).\nAcute toxicity — inhalation (Section 3.1)\n1, 2\n—\nif immediate administration of antidote is required.\n… Reference to supplemental first aid instruction.\nP321\nSpecific treatment (see … on this label).\nAcute toxicity — oral (Section 3.1)\n1, 2, 3\n—\nif immediate administration of antidote is required.\n… Reference to supplemental first aid instruction.\nAcute toxicity, dermal (Section 3.1)\n1, 2, 3, 4\n—\nif immediate measures such as specific cleansing agent are advised.\n… Reference to supplemental first aid instruction.\nAcute toxicity — inhalation (Section 3.1)\n3\n—\nif immediate specific measures are required.\n… Reference to supplemental first aid instruction.\nSkin corrosion (Section 3.2)\n1, 1A, 1B, 1C\n… Reference to supplemental first aid instruction.\nManufacturer/supplier may specify a cleansing agent if appropriate.\nSkin irritation (Section 3.2)\n2\nSkin sensitisation (Section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure (Section 3.8)\n1\n—\nif immediate measures are required.\n… Reference to supplemental first aid instruction.\nP330\nRinse mouth.\nAcute toxicity — oral (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nP331\nDo NOT induce vomiting.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nAspiration hazard (section 3.10)\n1\nP332\nIf skin irritation occurs:\nSkin irritation (section 3.2)\n2\nmay be omitted if P333 is given on the label.\nP333\nIf skin irritation or rash occurs:\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP334\nImmerse in cool water [or wrap in wet bandages].\nPyrophoric liquids (Section 2.9)\n1\n—\ntext in square brackets to be used for pyrophoric liquids and solids\nPyrophoric solids (Section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2\nUse only ‘ immerse in cool water. ’ Text in square brackets should not be used.\nP335\nBrush off loose particles from skin.\nPyrophoric solids (section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2\nP336\nThaw frosted parts with lukewarm water. Do not rub affected area.\nGases under pressure (section 2.5)\nRefrigerated liquefied gas\nP337\nIf eye irritation persists:\nEye irritation (section 3.3)\n2\nP338\nRemove contact lenses, if present and easy to do. Continue rinsing.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSerious eye damage/eye irritation (section 3.3)\n1\nEye irritation (section 3.3)\n2\nP340\nRemove person to fresh air and keep comfortable for breathing.\nAcute toxicity — inhalation (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (section 3.8)\n3\nP342\nIf experiencing respiratory symptoms:\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nP351\nRinse cautiously with water for several minutes.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSerious eye damage/eye irritation (section 3.3)\n1\nEye irritation (section 3.3)\n2\nP352\nWash with plenty of water/…\nAcute toxicity — dermal (section 3.1)\n1, 2, 3, 4\n…Manufacturer/supplier may specify a cleansing agent if appropriate, or may recommend an alternative agent in exceptional cases if water is clearly inappropriate.\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP353\nRinse skin with water [or shower].\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\ntext in square brackets to be included where the manufacturer/supplier considers it appropriate for the specific chemical.\nSkin corrosion (Section 3.2)\n1, 1A, 1B, 1C\nP360\nRinse immediately contaminated clothing and skin with plenty of water before removing clothes.\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nP361\nTake off immediately all contaminated clothing.\nFlammable liquids (section 2.6)\n1, 2, 3\nAcute toxicity — dermal (section 3.1)\n1, 2, 3\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nP362\nTake off contaminated clothing.\nAcute toxicity, dermal (section 3.1)\n4\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP363\nWash contaminated clothing before reuse.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nP364\nAnd wash it before reuse.\nAcute toxicity, dermal (section 3.1)\n1, 2, 3, 4\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP370\nIn case of fire:\nExplosives (section 2.1)\nUnstable explosives and divisions 1.1, 1.2, 1.3, 1.4, 1.5\nOxidising gases (section 2.4)\n1\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic Peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3\nP371\nIn case of major fire and large quantities:\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nDesensitised explosives (section 2.17)\n4\nP372\nExplosion risk.\nExplosives (Section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, and 1.5\nDivision 1.4\n—\nexcept for explosives of division 1.4 (compatibility group S) in transport packaging.\nSelf-reactive substances and mixtures (Section 2.8)\nType A\nOrganic peroxides (Section 2.15)\nType A\nP373\nDO NOT fight fire when fire reaches explosives.\nExplosives (Section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.5\nDivision 1.4\n—\nexcept for explosives of division 1.4 (compatibility group S) in transport packaging.\nSelf-reactive substances and mixtures (Section 2.8)\nType A\nOrganic peroxides (Section 2.15)\nType A\nP375\nFight fire remotely due to the risk of explosion.\nExplosives (section 2.1)\nDivision 1.4\nfor explosives of division 1.4 (compatibility group S) in transport packaging.\nSelf-reactive substances and mixtures (section 2.8)\nType B\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nOrganic peroxides (section 2.15)\nType B\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nP376\nStop leak if safe to do so.\nOxidising gases (section 2.4)\n1\nP377\nLeaking gas fire: Do not extinguish, unless leak can be stopped safely.\nFlammable gases (section 2.2)\n1A, 1B, 2\nP378\nUse … to extinguish.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nif water increases risk\n… Manufacturer/supplier to specify appropriate media\nFlammable solids (Section 2.7)\n1, 2\nSelf-reactive substances and mixtures (Section 2.8)\nTypes B, C, D, E, F\nPyrophoric liquids (Section 2.9)\n1\nPyrophoric solids (Section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2, 3\nOxidising liquids (Section 2.13)\n1, 2, 3\nOxidising solids (Section 2.14)\n1, 2, 3\nOrganic peroxides (Section 2.15)\nTypes B, C, D, E, F\nP380\nEvacuate area.\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nOrganic peroxides (section 2.15)\nTypes A, B\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nP381\nIn case of leakage, eliminate all ignition sources\nFlammable gases (section 2.2)\n1A, 1B, 2\nP390\nAbsorb spillage to prevent material damage.\nCorrosive to metals (section 2.16)\n1\nP391\nCollect spillage.\nHazardous to the aquatic environment – acute aquatic hazard (section 4.1)\n1\nHazardous to the aquatic environment – long-term aquatic hazard (section 4.1)\n1, 2\nP301 + P310\nIF SWALLOWED: Immediately call a POISON CENTER/doctor/…\nAcute toxicity — oral (section 3.1)\n1, 2, 3\n…Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nAspiration hazard (section 3.10)\n1\nP301 + P312\nIF SWALLOWED: Call a POISON CENTER/doctor/… if you feel unwell\nAcute toxicity – oral (section 3.1)\n4\n… Manufacturer/supplier to specify the appropriate source of emergency medical advice\nP302 + P334\nIF ON SKIN: Immerse in cool water or wrap in wet bandages.\nPyrophoric liquids (Section 2.9)\n1\nP302 + P352\nIF ON SKIN: Wash with plenty of water/…\nAcute toxicity — dermal (section 3.1)\n1, 2, 3, 4\n…Manufacturer/supplier may specify a cleansing agent if appropriate, or may recommend an alternative agent in exceptional cases if water is clearly inappropriate.\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP304 + P340\nIF INHALED: Remove person to fresh air and keep comfortable for breathing.\nAcute toxicity — inhalation (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSpecific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (section 3.8)\n3\nP306 + P360\nIF ON CLOTHING: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nP308 + P311\nIF exposed or concerned: Call a POISON CENTER/doctor/…\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\n…Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nP308 + P313\nIF exposed or concerned: Get medical advice/attention.\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nP332 + P313\nIf skin irritation occurs: Get medical advice/attention.\nSkin irritation (Section 3.2)\n2\n—\nmay be omitted when P333 + P313 is given on the label.\nP333 + P313\nIf skin irritation or rash occurs: Get medical advice/attention.\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP336 + P315\nThaw frosted parts with lukewarm water. Do not rub affected area. Get immediate medical advice/attention.\nGases under pressure (Section 2.5)\nRefrigerated liquefied gas\nP337 + P313\nIf eye irritation persists: Get medical advice/attention.\nEye irritation (section 3.3)\n2\nP342 + P311\nIf experiencing respiratory symptoms: Call a POISON CENTER/doctor/…\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\n…Manufacturer/supplier to specify the appropriate source of emergency medical advice.\nP361 + P364\nTake off immediately all contaminated clothing and wash it before reuse.\nAcute toxicity, dermal (section 3.1)\n1, 2, 3\nP362 + P364\nTake off contaminated clothing and wash it before reuse.\nAcute toxicity, dermal (section 3.1)\n4\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nP370 + P376\nIn case of fire: Stop leak if safe to do so.\nOxidizing gases (section 2.4)\n1\nP370 + P378\nIn case of fire: Use … to extinguish.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nif water increases risk.\n… Manufacturer/sup-plier to specify appropriate media.\nFlammable solids (Section 2.7)\n1, 2\nSelf-reactive substances and mixtures (Section 2.8)\nTypes C, D, E, F\nPyrophoric liquids (Section 2.9)\n1\nPyrophoric solids (Section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2, 3\nOxidising liquids (Section 2.13)\n1, 2, 3\nOxidising solids (Section 2.14)\n1, 2, 3\nOrganic peroxides (Section 2.15)\nTypes C, D, E, F\nP301 + P330 + P331\nIF SWALLOWED: Rinse mouth. Do NOT induce vomiting.\nSkin corrosion (Section 3.2)\n1, 1A, 1B, 1C\nP302 + P335 + P334\nIF ON SKIN: Brush off loose particles from skin. Immerse in cool water [or wrap in wet bandages].\nPyrophoric solids (Section 2.10)\n1\n—\ntext in square brackets to be used for pyrophoric solids\nSubstances and mixtures which, in contact with water, emit flammable gases (Section 2.12)\n1, 2\n—\nuse only ‘ Immerse in cold water ’ . Text in square brackets should not be used.\nP303 + P361 + P353\nIF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\ntext in square brackets to be included where the manufacturer/supplier considers it appropriate for the specific chemical.\nSkin corrosion (Section 3.2)\n1, 1A, 1B, 1C\nP305 + P351 + P338\nIF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.\nSkin corrosion (Section 3.2)\n1, 1A, 1B, 1C\nSerious eye damage/eye irritation (Section 3.3)\n1\nEye irritation (Section 3.3)\n2\nP370 + P380 + P375\nIn case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.\nExplosives (section 2.1)\nDivision 1.4\nfor explosives of division 1.4 (compatibility group S) in transport packaging\nDesensitised explosives (section 2.17)\n1, 2, 3\nP371 + P380 + P375\nIn case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nDesensitised explosives (section 2.17)\n4\nP370 + P372 + P380 + P373\nIn case of fire: Explosion risk. Evacuate area. DO NOT fight fire when fire reaches explosives\nExplosives (Section 2.1)\nUnstable explosives and divisions 1.1, 1.2, 1.3, 1.5\nDivision 1.4\n—\nexcept for explosives of division 1.4 (compatibility group S) in transport packaging.\nSelf-reactive substances and mixtures (Section 2.8)\nType A\nOrganic peroxides (Section 2.15)\nType A\nP370 + P380 + P375 + [P378]\nIn case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. [Use … to extinguish].\nSelf-reactive substances and mixtures (Section 2.8)\nType B\n—\ntext in square brackets to be used if water increases risk.\n… Manufacturer/supplier to specify appropriate media.\nOrganic peroxides (Section 2.15)\nType B\nTable 6.4\nPrecautionary statements — Storage\nCode\nStorage precautionary statements\nHazard class\nHazard category\nConditions for use\n(1)\n(2)\n(3)\n(4)\n(5)\nP401\nStore in accordance with …\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\n… Manufacturer/supplier to specify local/regional/national/international regulations as applicable.\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nP402\nStore in a dry place.\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nP403\nStore in a well-ventilated place.\nFlammable gases (section 2.2)\n1A, 1B, 2\nOxidising gases (section 2.4)\n1\nGases under pressure (section 2.5)\nCompressed gas\nLiquefied gas\nRefrigerated liquefied gas\nDissolved gas\nFlammable liquids (section 2.6)\n1, 2, 3\nfor flammable liquids Category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere.\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nexcept for temperature controlled self-reactive substances and mixtures or organic peroxides because condensation and consequent freezing may take place.\nOrganic peroxides (section 2.15)\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nif the substance or mixture is volatile and may generate a hazardous atmosphere.\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\nP404\nStore in a closed container.\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nP405\nStore locked up.\nAcute toxicity — oral (section 3.1)\n1, 2, 3\nAcute toxicity — dermal (section 3.1)\n1, 2, 3\nAcute toxicity — inhalation (section 3.1)\n1, 2, 3\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nSpecific target organ toxicity — single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (section 3.8)\n3\nAspiration hazard (section 3.10)\n1\nP406\nStore in a corrosion-resistant/… container with a resistant inner liner.\nCorrosive to metals (Section 2.16)\n1\n—\nmay be omitted if P234 is given on the label\n… Manufacturer/supplier to specify other compatible materials.\nP407\nMaintain air gap between stacks or pallets.\nSelf-heating substances and mixtures (Section 2.11)\n1, 2\nP410\nProtect from sunlight.\nAerosols (section 2.3)\n1,2, 3\nGases under pressure (section 2.5)\nCompressed gas\nLiquefied gas\nDissolved gas\n—\nmay be omitted for gases filled in transportable gas cylinders in accordance with packing instruction P200 of the UN RTDG, Model Regulations, unless those gases are subject to (slow) decomposition or polymerisation\nSelf-heating substances and mixtures (section 2.11)\n1, 2\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nP411\nStore at temperatures not exceeding … °C/… °F.\nSelf-reactive substances and mixtures (Section 2.8)\nTypes A, B, C, D, E, F\n—\nif temperature control is required (according to Annex I, Section 2.8.2.4 or 2.15.2.3) or if otherwise deemed necessary.\n… Manufacturer/supplier to specify temperature using the applicable temperature scale.\nOrganic peroxides (Section 2.15)\nTypes A, B, C, D, E, F\nP412\nDo not expose to temperatures exceeding 50 °C/ 122 °F.\nAerosols (Section 2.3)\n1, 2, 3\nManufacturer/supplier to use applicable temperature scale.\nP413\nStore bulk masses greater than … kg/… lbs at temperatures not exceeding … °C/… °F.\nSelf-heating substances and mixtures (Section 2.11)\n1, 2\n… Manufacturer/supplier to specify mass and temperature using applicable scale.\nP420\nStore separately.\nSelf-reactive substances and mixtures (Section 2.8)\nTypes A, B, C, D, E, F\nSelf-heating substances and mixtures (Section 2.11)\n1,2\nOxidising liquids (Section 2.13)\n1\nOxidising solids (Section 2.14)\n1\nOrganic peroxides (Section 2.15)\nTypes A,B,C,D,E,F\nP402 + P404\nStore in a dry place. Store in a closed container.\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nP403 + P233\nStore in a well-ventilated place. Keep container tightly closed.\nAcute toxicity — inhalation (Section 3.1)\n1, 2, 3\n—\nif the substance or mixture is volatile and may generate a hazardous atmosphere.\nSpecific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)\n3\nSpecific target organ toxicity — single exposure; narcosis (Section 3.8)\n3\nP403 + P235\nStore in a well-ventilated place. Keep cool.\nFlammable liquids (Section 2.6)\n1, 2, 3\n—\nfor flammable liquids Category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere.\nP410 + P403\nProtect from sunlight. Store in a well-ventilated place.\nGases under pressure (Section 2.5)\nCompressed gas\n—\nP410 may be omitted for gases filled in transportable gas cylinders in accordance with packing instruction P200 of the UN RTDG, unless those gases are subject to (slow) decomposition or polymerisation.\nLiquefied gas\nDissolved gas\nP410 + P412\nProtect from sunlight. Do not expose to temperatures exceeding 50 °C/122 °F.\nAerosols (Section 2.3)\n1, 2, 3\nManufacturer/ supplier to use applicable temperature scale.\nTable 6.5\nPrecautionary statements — Disposal\nCode\nDisposal precautionary statements\nHazard class\nHazard category\nConditions for use\n(1)\n(2)\n(3)\n(4)\n(5)\nP501\nDispose of contents/container to …\nFlammable liquids (section 2.6)\n1, 2, 3\n… in accordance with local/regional/national/international regulation (to be specified).\nManufacturer/supplier to specify whether disposal requirements apply to contents, container or both.\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – oral (section 3.1)\n1, 2, 3, 4\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nSkin corrosion (section 3.2)\n1, 1A, 1B, 1C\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nSpecific target organ toxicity – single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\nSpecific target organ toxicity – repeated exposure (section 3.9)\n1, 2\nAspiration hazard (section 3.10)\n1\nHazardous to the aquatic environment – acute aquatic hazard (section 4.1)\n1\nHazardous to the aquatic environment – chronic aquatic hazard (section 4.1)\n1, 2, 3, 4\nP502\nRefer to manufacturer or supplier for information on recovery or recycling\nHazardous to the ozone layer (Section 5.1)\n1\nP503\nRefer to manufacturer/ supplier/… for information on disposal/recovery/ recycling\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\n… Manufacturer/supplier to specify appropriate source of information in accordance with local/regional/national/international regulations as applicable.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Substituted by Commission Regulation (EU) 2019/521 of 27 March 2019 amending, for the purposes of its adaptation to technical and scientific progress Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F2",
      "text": "Substituted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F3",
      "text": "Inserted by Commission Regulation (EU) 2019/521 of 27 March 2019 amending, for the purposes of its adaptation to technical and scientific progress Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F4",
      "text": "Substituted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F5",
      "text": "Deleted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F6",
      "text": "Substituted by Commission Regulation (EU) No 286/2011 of 10 March 2011 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F7",
      "text": "Deleted by Commission Regulation (EU) No 286/2011 of 10 March 2011 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F8",
      "text": "Deleted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F9",
      "text": "Inserted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F10",
      "text": "Inserted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2008/1272/annex/IV/division/1",
    "retrieved_at": "2026-11-01T14:51:47.470832+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}