{
  "url": "https://openlegislation.uk/eu-regulation-2008-429/annex-III/division-6/division-6.3/division-6.3.2/division-6.3.2.3",
  "json_url": "https://openlegislation.uk/eu-regulation-2008-429/annex-III/division-6/division-6.3/division-6.3.2/division-6.3.2.3.json",
  "legislation": "eur/2008/429",
  "legislation_title": "Commission Regulation (EC) No 429/2008 of 25 April 2008 on detailed rules for the implementation of Regulation (EC) No 1831/2003 of the European Parliament and of the Council as regards the preparation and the presentation of applications and the assessment and the authorisation of feed additives (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2008-429",
  "path": "annex/III/division/6/division/6.3/division/6.3.2/division/6.3.2.3",
  "kind": "division",
  "number": "6.3.2.3",
  "heading": "Assessment of consumer safety",
  "text": "Proposal for Maximum Residue Limits (MRLs)\nSetting of MRLs can be done by assuming that no significant differences in the content of residues occur in the edible tissues of minor species compared to a similar major species.\nMRLs can be extrapolated within classes of animals as follows:\nfrom major growing ruminants to all growing ruminants;\nfrom milk of dairy cows to milk of other dairy ruminants;\nfrom pigs to all monogastric mammals, excluding horses;\nfrom chickens or turkeys to other poultry;\nfrom laying hens to other laying birds; and\nfrom Salmonidae to all fin fish.\nMRLs for horses could be extrapolated when MRLs for a major ruminant and a major monogastric mammal exist.\nIf identical MRLs were derived in cattle (or sheep), pigs and chicken (or poultry), which represent major species with different metabolic capacities and tissue composition, the same MRLs can also be set for ovine, equidae and rabbits, which means an extrapolation is considered possible to all food-producing animals except fish. Considering the Committee for Medicinal Products for Veterinary Use (CVMP) guideline on the establishment of MRLs for Salmonidae and other finfish, which already allows an extrapolation from MRLs in muscle of a major species to Salmonidae and other finfish provided that the parent substances is acceptable as marker residue for the MRL in muscle and skin, MRLs can be extrapolated to all-food-producing animals.\nAnalytical methods shall be available for monitoring residues in edible tissue and products of all food-producing animals.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "footnote",
      "label": "f1",
      "text": "Note for guidance of the establishment of maximum residue limits for Salmonidae and other fin fish. The European Agency for the Evaluation of Medicinal Products. Veterinary Medicines Evaluation Unit. EMEA/CVMP/153b/97-FINAL."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2008/429/annex/III/division/6/division/6.3/division/6.3.2/division/6.3.2.3",
    "retrieved_at": "2026-11-01T14:52:17.021143+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}