# Commission Regulation (EC) No 429/2008 of 25 April 2008 on detailed rules for the implementation of Regulation (EC) No 1831/2003 of the European Parliament and of the Council as regards the preparation and the presentation of applications and the assessment and the authorisation of feed additives (Text with EEA relevance), Division 6.3.2.3: Assessment of consumer safety

Extent: E+W+S+N.I.

Proposal for Maximum Residue Limits (MRLs)
Setting of MRLs can be done by assuming that no significant differences in the content of residues occur in the edible tissues of minor species compared to a similar major species.
MRLs can be extrapolated within classes of animals as follows:
from major growing ruminants to all growing ruminants;
from milk of dairy cows to milk of other dairy ruminants;
from pigs to all monogastric mammals, excluding horses;
from chickens or turkeys to other poultry;
from laying hens to other laying birds; and
from Salmonidae to all fin fish.
MRLs for horses could be extrapolated when MRLs for a major ruminant and a major monogastric mammal exist.
If identical MRLs were derived in cattle (or sheep), pigs and chicken (or poultry), which represent major species with different metabolic capacities and tissue composition, the same MRLs can also be set for ovine, equidae and rabbits, which means an extrapolation is considered possible to all food-producing animals except fish. Considering the Committee for Medicinal Products for Veterinary Use (CVMP) guideline on the establishment of MRLs for Salmonidae and other finfish, which already allows an extrapolation from MRLs in muscle of a major species to Salmonidae and other finfish provided that the parent substances is acceptable as marker residue for the MRL in muscle and skin, MRLs can be extrapolated to all-food-producing animals.
Analytical methods shall be available for monitoring residues in edible tissue and products of all food-producing animals.

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Source: https://www.legislation.gov.uk/eur/2008/429/annex/III/division/6/division/6.3/division/6.3.2/division/6.3.2.3 (the official version)
Page: https://openlegislation.uk/eu-regulation-2008-429/annex-III/division-6/division-6.3/division-6.3.2/division-6.3.2.3
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.