Division 5.1.1 F1

An active substance, other than a micro-organism, shall not be considered as being of low-risk where it corresponds to any of the following:

1. (a)

   it is or has to be classified in accordance with Regulation (EC) No 1272/2008 as any of the following:

   • carcinogenic category 1A, 1B or 2,

   • mutagenic category 1A, 1B or 2,

   • toxic to reproduction category 1A, 1B or 2,

   • skin sensitiser category 1,

   • serious damage to eye category 1,

   • respiratory sensitiser category 1,

   • acute toxicity category 1, 2 or 3,

   • specific Target Organ Toxicant, category 1 or 2,

   • toxic to aquatic life of acute and chronic category 1 on the basis of appropriate standard tests,

   • explosive,

   • skin corrosive, category 1A, 1B or 1C;

2. (b)

   it has been identified as priority substance F2and is listed in Annex 10 to Directive 2000/60/EC;

3. (c)

   it is deemed to be an endocrine disruptor;

4. (d)

   it has neurotoxic or immunotoxic effects.