{
  "url": "https://openlegislation.uk/eu-regulation-2009-761/annex-IV/division-4",
  "json_url": "https://openlegislation.uk/eu-regulation-2009-761/annex-IV/division-4.json",
  "legislation": "eur/2009/761",
  "legislation_title": "Commission Regulation (EC) No 761/2009 of 23 July 2009 amending, for the purpose of its adaptation to technical progress, Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2009-761",
  "path": "annex/IV/division/4",
  "kind": "division",
  "number": "4",
  "heading": "LITERATURE",
  "text": "(1) OECD TG 201 (2006). Freshwater Alga and Cyanobacteria, Growth Inhibition Test.\n(2) ISO 1998: Water quality — Guidance for algal growth inhibition tests with poorly soluble materials, volatile compounds, metals and waster water. ISO/DIS 14442.\n(3) OECD 2000: Guidance Document on Aquatic Toxicity Testing of Difficult Substances and mixtures. Environmental Health and Safety Publications. Series on Testing and Assessment, no. 23.\n(4) ISO 1998: Water quality — Sampling — Part 16: General Guidance for Biotesting. ISO 5667-16.\n(5) ISO 1993: Water quality — Algal growth inhibition test. ISO 8692.\n(6) Mayer, P., Cuhel, R. and Nyholm, N. (1997). A simple in vitro fluorescence method for biomass measurements in algal growth inhibition tests. Water Research 31: 2525-2531.\n(7) Slovacey, R.E. and Hanna, P.J. In vivo fluorescence determinations of phytoplancton chlorophyll, Limnology & Oceanography 22,5 (1977), pp.919-925.\n(8) Simpson, S.L., Roland, M.G.E., Stauber, J.L. and Batley, G.E. (2003). Effect of declining toxicant concentrations on algal bioassay endpoints. Environ. Toxicol. Chem 22, 2073-2079.\n(9) Christensen, E.R., Nyholm, N. (1984): Ecotoxicological Assays with Algae: Weibull Dose-Response Curves. Env. Sci. Technol. 19, 713-718.\n(10) Nyholm, N. Sørensen, P.S., Kusk, K.O. and Christensen, E.R. (1992): Statistical treatment of data from microbial toxicity tests. Environ. Toxicol. Chem. 11, 157-167.\n(11) Bruce, R.D., and Versteeg, D.J. (1992). A statistical procedure for modelling continuous toxicity data. Env. Toxicol. Chem. 11:1485-1494.\n(12) OECD. (2004). Guidance Document on Statistical Analysis of Ecotoxicity Data.\n(13) Norberg-King T.J. (1988). An interpolation estimate for chronic toxicity: The ICp approach. National Effluent Toxicity Assessment Center Technical Report 05-88. USEPA, Duluth, MN.\n(14) Dunnett, C.W. (1955). A multiple comparisons procedure for comparing several treatments with a control. J. Amer. Statist. Assoc. 50: 1096-1121\n(15) Dunnett, C.W. (1964). New tables for multiple comparisons with a control. Biometrics 20: 482-491.\n(16) Williams, D.A. (1971). A test for differences between treatment means when several dose levels are compared with a zero dose control. Biometrics 27: 103-117.\n(17) Williams, D.A. (1972). The comparison of several dose levels with a zero dose control. Biometrics 28: 510-531.\n(18) Draper, N.R. and Smith, H. (1981). Applied Regression Analysis, second edition. Wiley, New York.\n(19) Brain P. and Cousens R. (1989). An equation to describe dose-responses where there is stimulation of growth at low doses. Weed Research, 29, 93-96.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2009/761/annex/IV/division/4",
    "retrieved_at": "2026-11-01T14:51:19.625001+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}