# Commission Regulation (EU) No 291/2011 of 24 March 2011 on essential uses of controlled substances other than hydrochlorofluorocarbons for laboratory and analytical purposes in the Union under Regulation (EC) No 1005/2009 of the European Parliament and of the Council on substances that deplete the ozone layer, Division 1: The following uses of controlled substances other than hydrochlorofluorocarbons are considered as essential laboratory and analytical uses:

Extent: E+W+S+N.I.

(a) the use of controlled substances as a reference or standard:
to calibrate equipment which uses controlled substances,
to monitor emission levels of controlled substances,
to determine residue levels of controlled substances in goods, plants and commodities;
(b) the use of controlled substances in laboratory toxicological studies;
(c) laboratory uses in which the controlled substance is transformed in a chemical reaction like controlled substances used as feedstock;
(d) the use of methyl bromide inside a laboratory to compare the efficacy of methyl bromide and its alternatives;
(e) the use of carbon tetrachloride as a solvent for bromination reactions involving N-bromosuccineimide;
(f) the use of carbon tetrachloride as chain transfer agent in free-radical polymerisation reactions;
(g) any other laboratory and analytical use for which a technically and economically feasible alternative is not available.

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Source: https://www.legislation.gov.uk/eur/2011/291/annex/division/1 (the official version)
Page: https://openlegislation.uk/eu-regulation-2011-291/annex/division-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.