{
  "url": "https://openlegislation.uk/eu-regulation-2011-540/annex-1/part-E",
  "json_url": "https://openlegislation.uk/eu-regulation-2011-540/annex-1/part-E.json",
  "legislation": "eur/2011/540",
  "legislation_title": "Commission Implementing Regulation (EU) No 540/2011 of 25 May 2011 implementing Regulation (EC) No 1107/2009 of the European Parliament and of the Council as regards the list of approved active substances (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2011-540",
  "path": "annex/1/part/E",
  "kind": "part",
  "number": "E",
  "heading": "Candidates for substitution",
  "text": "Further details on identity and specification of active substance are provided in the review report.\nCommission Regulation (EU) 2018/605 of 19 April 2018 amending Annex II to Regulation (EC) No 1107/2009 by setting out scientific criteria for the determination of endocrine disrupting properties. (OJ L 101, 20.4.2018, p. 33).\nCommon Name, Identification Numbers\nIUPAC Name\nPurity\nDate of approval\nExpiration of approval\nSpecific provisions\n1\nFlumetralin\nCAS No 62924-70-3\nCIPAC No 971\nN -(2-chloro-6-fluorobenzyl)- N -ethyl-α,α,α-trifluoro-2,6-dinitro- p -toluidine\n980 g/kg\nThe impurity Nitrosamine (calculated as nitroso-dimethylamine) shall not exceed 0,001 g/kg in the technical material.\n11 December 2015\n11 December 2022\nFor the implementation of the uniform principles as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on flumetralin, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to:\n(a)the protection of operators and workers, ensuring that conditions of use include the application of adequate personal protective equipment, where appropriate;\n(b)the protection of groundwater, when the substance is applied in regions with vulnerable soil and/or climatic conditions;\n(c)the risk to herbivorous mammals;\n(d)the risk to aquatic organisms.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit confirmatory information as regards:\n1..the technical specification of the active substance as manufactured (based on commercial scale production);\n2..the compliance of the toxicity batches with the confirmed technical specification.\nThe applicant shall submit to the Commission, the Member States and the Authority the information referred to in points 1 and 2 by 11 June 2016.\n2\nEsfenvalerate\nCAS No: 66230-04-4\nCIPAC No: 481\n(αS)-α-cyano-3-phenoxybenzyl (2S)-2-(4-chlorophenyl)-3-methylbutyrate\n830 g/kg\nThe impurity toluene shall not exceed 10 g/kg in the technical material.\n1 January 2016\n31 December 2022\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on esfenvalerate, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to:\nthe risk from esfenvalerate and the 2SαR-isomer of fenvalerate to aquatic organisms including the risk for bio-accumulation through the food chain,\nthe risk to honeybees and non-target arthropods,\nthe protection of groundwater, when the substance is applied in regions with vulnerable soil and/or climatic conditions.\nConditions of use shall include risk mitigation measures, where appropriate.\n3\nMetsulfuron-methyl\nCAS No 74223-64-6\nCIPAC No 441.201\nMethyl 2-(4-methoxy-6-methyl-1,3,5-triazin-2-ylcarbamoylsulfamoyl)benzoate\n967 g/kg\n1 April 2016\n31 March 2023\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on metsulfuron-methyl, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to:\nthe protection of consumers,\nthe protection of groundwater,\nthe protection of non-target terrestrial plants.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit to the Commission, the Member States and the Authority by 30 September 2016 confirmatory information as regards the genotoxic potential of the metabolite triazine-amine (IN-A4098) to confirm that this metabolite is not genotoxic and not relevant for risk assessment.\n4\nBenzovindiflupyr\nCAS No: 1072957-71-1\nCIPAC No: not available\nN -[(1 RS ,4 SR )-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide\n960 g/kg (50/50) racemate\n2.3.2016\n2.3.2023\nFor the implementation of the uniform principles as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on benzovindiflupyr, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to the risk to aquatic organisms.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit confirmatory information as regards:\n(1)the technical specification of the active substance as manufactured (based on commercial scale production) including the relevance of impurities;\n(2)the compliance of the toxicity and ecotoxicity batches with the confirmed technical specification;\n(3)the effect of water treatment processes on the nature of residues present in surface water and groundwater, when surface water or groundwater is abstracted for drinking water.\nThe applicant shall submit to the Commission, the Member States and the Authority the information requested under points (1) and (2) by 2 September 2016 and the information requested under point (3) within two years after adoption of a guidance document on evaluation of the effect of water treatment processes on the nature of residues present in surface and groundwater.\n5\nLambda-Cyhalothrin\nCAS No 91465-08-6\nCIPAC No 463\nA 1:1 mixture of:\n(R)-α-cyano-3-phenoxybenzyl (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate and (S)-α-cyano-3-phenoxybenzyl (1R,3R)-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate or of (R)-α-cyano-3-phenoxybenzyl (1S)-cis-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate and (S)-α-cyano-3-phenoxybenzyl (1R)-cis-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate\n900 g/kg\n1 April 2016\n31 March 2023\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on lambda-cyhalothrin, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to the:\n(a)protection of operators, workers and bystanders;\n(b)metabolites potentially formed in processed commodities;\n(c)risk to aquatic organisms, mammals and non-target arthropods.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicants shall submit confirmatory information as regards:\n1..a systematic review to assess the evidence available as regards potential sperm effects linked to exposure to lambda-cyhalothrin using guidance available (e.g. EFSA GD on Systematic Review methodology, 2010);\n2..toxicological information to assess the toxicological profile of the metabolites V (PBA) and XXIII (PBA(OH)).\nThe applicants shall submit those information to the Commission, the Member States and the Authority by 1 April 2018.\n6\nProsulfuron\nCAS No 94125-34-5\nCIPAC No 579\n1-(4-methoxy-6-methyl-triazin-2-yl)-3-[2-(3,3,3- trifluoropropyl)-phenylsulfonyl]-urea\n950 g/kg\nThe impurity 2-(3,3,3-trifluoro-propyl)-benzene sulphonamide shall not exceed 10 g/kg in the technical material.\n1 May 2017\n30 April 2024\nPART A\nUse shall be limited to one application every three years on the same field at a maximum dose of 20 g active substance per hectare.\nPART B\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on prosulfuron, and in particular Appendices I and II thereof, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to:\nthe protection of groundwater, when the substance is applied in regions with vulnerable soil and/or climatic conditions;\nthe risk to non-target terrestrial and aquatic plants.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit confirmatory information as regards the genotoxic potential of the metabolite triazine-amine (CGA150829) to confirm that this metabolite is not genotoxic and not relevant for risk assessment.\nThe applicant shall submit that information to the Commission, the Member States and the Authority by 31 October 2017.\n7\nPendimethalin\nCAS No 40487-42-1\nCIPAC No 357\nN-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene\n900 g/kg\n1,2-dichloroethane\n≤ 1 g/kg\nTotal N-Nitroso compounds: max 100 ppm, of which N-Nitroso-pendimethalin: < 45 ppm.\n1 September 2017\n31 August 2024\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on pendimethalin, and in particular Appendices I and II thereof, shall be taken into account.\nIn their overall assessment Member States shall pay particular attention to:\nthe specification of the technical material as commercially manufactured, which must be confirmed and supported by appropriate analytical data. The test material used in the toxicity dossiers shall be compared and verified against the specification of the technical material,\nthe protection of operators,\nthe protection of birds, mammals and aquatic organisms.\nConditions of use shall include risk mitigation measures, where appropriate.\nIn particular, personal protective equipment such as gloves, coverall and sturdy footwear has to be worn to ensure that the AOEL is not exceeded for the operator.\nThe applicant shall submit confirmatory information to the Commission, the Member States and the Authority as regards:\n1..the potential for bioaccumulation, in particular a reliable BCF value for bluegill sunfish ( Lepomis macrochirus );\n2..the effect of water treatment processes on the nature of residues present in surface and groundwater, when surface water or groundwater are abstracted for drinking water.\nThe applicant shall submit the confirmatory information requested under point 1 by 31 December 2018. The applicant shall submit the confirmatory information requested under point 2 within a period of two years of the publication by the Commission of a guidance document on evaluation of the effect of water treatment processes on the nature of residues present in surface and groundwater.\n8\nImazamox\nCAS No 114311-32-9\nCIPAC No 619\n2-[(RS)-4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl]-5-methoxymethylnicotinic acid\n≥ 950 g/kg\nThe impurity cyanide ion (CN – ) shall not exceed 5 mg/kg in the technical material.\n1 November 2017\n31 October 2024\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the renewal report on imazamox, and in particular Appendices I and II thereto, shall be taken into account.\nIn this overall assessment Member States shall pay particular attention to:\nthe protection of consumers;\nthe protection of aquatic plants and of non-target terrestrial plants;\nthe protection of groundwater, when the substance is applied in regions with vulnerable soil and/or climatic conditions.\nConditions of authorisation shall include risk mitigation measures and monitoring programs shall be initiated to verify potential groundwater contamination from imazamox and metabolites CL 312622 and CL 354825 in vulnerable zones, where appropriate.\n9\nPropyzamide\nCAS No 23950-58-5\nCIPAC No 315\n3,5-dichloro- N -(1,1-dimethylprop-2-ynyl) benzamide\n920 g/kg\n1 July 2018\n30 June 2025\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on propyzamide and in particular Appendices I and II thereof, shall be taken into account.\nIn their overall assessment Member States shall pay particular attention to:\nthe protection of operators,\nthe protection of groundwater in vulnerable areas,\nthe protection of birds, mammals, non-target plants, soil and aquatic organisms.\nConditions of use shall include risk mitigation measures, where appropriate.\nIn particular, personal protective equipment such as gloves, coverall and sturdy footwear has to be worn to ensure that the AOEL is not exceeded for the operator.\nThe applicant shall submit to the Commission, the Member States and the Authority confirmatory information as regards:\n1..the completion of assessment of toxicological profile of metabolites identified in significant concentration in primary and rotational crops;\n2..the soil degradation of major metabolite RH- 24580;\n3..the effect of water treatment processes on the nature of residues present in surface and groundwater, when surface water or groundwater are abstracted for drinking water.\nThe applicant shall submit the information mentioned under point (1) by 31 October 2018 and the information mentioned under point (2) by 30 April 2019. The applicant shall submit the confirmatory information mentioned in point (3) within two years after a guidance document on evaluation of the effect of water treatment processes on the nature of residues present in surface and groundwater be made public by the Commission.\n10\nCopper compounds:\n1 January 2019\n31 December 2025\nOnly uses resulting in a total application of maximum 28 kg of copper per hectare over a period of 7 years shall be authorised.\nFor the implementation of the uniform principles, as referred to in Article 29(6) of Regulation (EC) No 1107/2009 of the European Parliament and of the Council, the conclusions of the review report on copper compounds and in particular Appendices I and II thereto, shall be taken into account.\nIn their overall assessment Member States shall pay particular attention to:\nthe operator, worker and bystander safety and ensure that conditions of use prescribe the application of adequate personal protective equipment and other mitigation measures as appropriate;\nthe protection of water and non-target organisms. In relation to these identified risks, risk mitigation measures, such as buffer zones, shall be applied where appropriate;\nthe amount of active substance applied and ensure that the authorised amounts, in terms of rates and number of applications, do not exceed the minimum necessary to achieve the desired effects and do not cause any unacceptable effect on the environment taking into account background levels of copper at the application site, and, where the information is available, copper input from other sources. Member States may in particular decide to set a maximum annual application rate not exceeding 4 kg/ha of copper.\nCopper hydroxide CAS No 20427-59-2 CIPAC No 44.305\nCopper (II) hydroxide\n≥ 573 g/kg\nCopper oxychloride CAS No 1332-65-6 or 1332-40-7 CIPAC No 44.602\nDicopper chloride trihydroxide\n≥ 550 g/kg\nCopper oxide CAS No 1317-39-1 CIPAC No 44.603\nCopper oxide\n≥ 820 g/kg\nBordeaux mixture CAS No 8011-63-0 CIPAC No 44.604\nNot allocated\n≥ 245 g/kg\nTribasic copper sulphate CAS No 12527-76-3 CIPAC No 44.306\nNot allocated\n≥ 490 g/kg\nThe following impurities shall not exceed the following levels:\nArsenic max. 0,1 mg/g Cu\nCadmium max. 0,1 mg/g Cu\nLead max. 0,3 mg/g Cu\nNickel max. 1 mg/g Cu\nCobalt max. 3 mg/kg\nMercury max. 5 mg/kg\nChromium max. 100 mg/kg\nAntimony max. 7 mg/kg\n11\nMethoxyfenozide\nCAS No 161050-58-4\nCIPAC No 656\nN-tert-Butyl-N′-(3-methoxy-o-toluoyl)-3,5-xylohydrazide\n≥ 970 g/kg\nThe following impurities must not exceed the following levels in the technical material:\nTert-butylhydrazine < 0,001 g/kg\nRH-116267 < 2 g/kg\n1 April 2019\n31 March 2026\nOnly uses in greenhouses shall be authorised.\nFor the implementation of the uniform principles as referred to in Article 29(6) of Regulation (EC) No 1107/2009, the conclusions of the review report on methoxyfenozide, and in particular Appendices I and II thereto, shall be taken into account.\nIn their overall assessment Member States shall pay particular attention to:\nthe protection of groundwater when the substance is applied in regions with vulnerable soil and/or climate conditions;\nthe risk of accumulation in soil;\nthe protection of non-target arthropods, sediment dwelling and aquatic organisms;\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit to the Commission, the Member States and the Authority confirmatory information as regards:\n1..a comparative in vitro metabolism study on methoxyfenozide, by 1 April 2020;\n2..the effect of water treatment processes on the nature of residues present in surface and groundwater, when surface water or groundwater is abstracted for drinking water, within 2 years after adoption of a guidance document on evaluation of the effect of water treatment processes on the nature of residues present in surface and groundwater.\nThe applicant shall also provide an updated assessment of the information submitted and, where relevant, further information to confirm the absence of thyroid endocrine activity in accordance with Points 3.6.5 and 3.8.2 of Annex II of Regulation (EC) No 1107/2009, as amended by Commission Regulation (EU) 2018/605 by 1 February 2021.\n12\nalpha-cypermethrin\nCAS No 67375-30-8\nCIPAC No 454\nRacemate comprising:\n(R)-α-cyano-3-phenoxybenzyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-α-cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate\nor\n(R)-α-cyano-3 phenoxybenzyl-(1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate\nand (S)-α-cyano-3 phenoxybenzyl-(1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate\n≥ 980 g/kg\nThe manufacturing impurity hexane is considered to be of toxicological concern and must not exceed 1 g/kg in the technical material\n1 November 2019\n31 October 2026\nFor the implementation of the uniform principles, as referred to in Article 9(6) of Regulation (EC) No 1107/2009, the conclusions of the renewal report on alpha-cypermethrin, and in particular Appendices I and II thereto, shall be taken into account.In this overall assessment Member States shall pay particular attention to:\nthe protection of operators, ensuring that the conditions of use prescribe the application of adequate personal protective equipment;\nthe consumer risk assessment;\nthe protection of aquatic organisms, bees and non-target arthropods.\nConditions of use shall include risk mitigation measures, where appropriate.\nThe applicant shall submit to the Commission, the Member States and the Authority confirmatory information as regards:\n1..the toxicological profile of the metabolites bearing the 3-phenoxybenzoyl moiety;\n2..the potential relative toxicity of individual cypermethrin isomers, in particular the enantiomer (1S cis αR);\n3..the effect of water treatment processes on the nature of residues present in surface and groundwater, when surface water or groundwater is abstracted for drinking water;\n4..Points 3.6.5 and 3.8.2 of Annex II of Regulation (EC) No 1107/2009, as amended by Regulation (EU) 2018/605.\nThe applicant shall submit the information referred to in point 1 by 30 October 2020; the information referred to in point 2 within two years from the date of publication, by the Commission, of a guidance document on evaluation of isomer mixtures; and the information referred to in point 3 within two years from the date of publication, by the Commission, of a guidance document on evaluation of the effect of water treatment processes on the nature of residues present in surface and groundwater.\nAs regards Points 3.6.5 and 3.8.2 of Annex II of Regulation (EC) No 1107/2009, as amended by Regulation (EU) 2018/605 an updated assessment of the information already submitted and, where relevant, further information to confirm the absence of androgenic endocrine activity shall be submitted by 30 October 2021.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [
    {
      "type": "F",
      "label": "F1",
      "text": "Inserted by Commission Implementing Regulation (EU) 2015/2105 of 20 November 2015 approving the active substance flumetralin, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F2",
      "text": "Inserted by Commission Implementing Regulation (EU) 2019/158 of 31 January 2019 renewing the approval of the active substance methoxyfenozide, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F3",
      "text": "Inserted by Commission Implementing Regulation (EU) 2015/2047 of 16 November 2015 renewing the approval of the active substance esfenvalerate, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F4",
      "text": "Inserted by Commission Implementing Regulation (EU) 2016/139 of 2 February 2016 renewing the approval of the active substance metsulfuron-methyl, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F5",
      "text": "Inserted by Commission Implementing Regulation (EU) 2016/177 of 10 February 2016 approving the active substance benzovindiflupyr, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F6",
      "text": "Inserted by Commission Implementing Regulation (EU) 2016/146 of 4 February 2016 renewing the approval of the active substance lambda-cyhalothrin, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F7",
      "text": "Inserted by Commission Implementing Regulation (EU) 2017/375 of 2 March 2017 renewing the approval of the active substance prosulfuron, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F8",
      "text": "Inserted by Commission Implementing Regulation (EU) 2017/1114 of 22 June 2017 renewing the approval of the active substance pendimethalin, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F9",
      "text": "Inserted by Commission Implementing Regulation (EU) 2017/1531 of 7 September 2017 renewing the approval of the active substance imazamox, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F10",
      "text": "Inserted by Commission Implementing Regulation (EU) 2018/755 of 23 May 2018 renewing the approval of the active substance propyzamide, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F11",
      "text": "Inserted by Commission Implementing Regulation (EU) 2018/1981 of 13 December 2018 renewing the approval of the active substances copper compounds, as candidates for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "F",
      "label": "F12",
      "text": "Inserted by Commission Implementing Regulation (EU) 2019/1690 of 9 October 2019 renewing the approval of the active substance alpha-cypermethrin, as a candidate for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 (Text with EEA relevance)."
    },
    {
      "type": "footnote",
      "label": "f1",
      "text": "Further details on identity and specification of active substance are provided in the review report."
    },
    {
      "type": "footnote",
      "label": "f2",
      "text": "Commission Regulation (EU) 2018/605 of 19 April 2018 amending Annex II to Regulation (EC) No 1107/2009 by setting out scientific criteria for the determination of endocrine disrupting properties. (OJ L 101, 20.4.2018, p. 33)."
    }
  ],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2011/540/annex/1/part/E",
    "retrieved_at": "2026-11-01T14:50:07.354761+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}