{
  "url": "https://openlegislation.uk/eu-regulation-2011-546/annex/part-II/division-B/division-2/division-2.2/division-2.2.1/division-2.2.1.3",
  "json_url": "https://openlegislation.uk/eu-regulation-2011-546/annex/part-II/division-B/division-2/division-2.2/division-2.2.1/division-2.2.1.3.json",
  "legislation": "eur/2011/546",
  "legislation_title": "Commission Regulation (EU) No 546/2011 of 10 June 2011 implementing Regulation (EC) No 1107/2009 of the European Parliament and of the Council as regards uniform principles for evaluation and authorisation of plant protection products (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2011-546",
  "path": "annex/part/II/division/B/division/2/division/2.2/division/2.2.1/division/2.2.1.3",
  "kind": "division",
  "number": "2.2.1.3",
  "heading": null,
  "text": "The mode of action of the micro-organism shall be evaluated in as much detail as appropriate. The possible role of metabolites/toxins for the mode of action shall be evaluated and when identified, the minimal effective concentration for each active metabolite/toxin shall be established. Information on mode of action can be a very valuable tool in identifying potential risks. Aspects to be considered in the evaluation, are:\n(a)antibiosis;\n(b)induction of plant resistance;\n(c)interference with the virulence of a pathogenic target organism;\n(d)endophytic growth;\n(e)root colonisation;\n(f)competition of ecological niche (e.g. nutrients, habitats);\n(g)parasitisation;\n(h)invertebrate pathogenicity.",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2011/546/annex/part/II/division/B/division/2/division/2.2/division/2.2.1/division/2.2.1.3",
    "retrieved_at": "2026-11-01T14:50:05.430430+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}