Division 2.8.4.2

A plant protection product may give rise to toxic effects due to the action of toxins or co-formulants. For the assessment of such effects the following information shall be taken into consideration:

1. (a)

   studies on toxicity to arthropods;

2. (b)

   information on fate and behaviour in the various parts of the environment;

3. (c)

   available data from biological primary screening.

If mortality or signs of intoxication are observed in the tests the evaluation must include a calculation of toxicity/exposure ratios based on the quotient of the ER₅₀ value (effective rate) and the estimated exposure.