# Regulation (EU) No 528/2012 of the European Parliament and of the Council of 22 May 2012 concerning the making available on the market and use of biocidal products (Text with EEA relevance), Division 27

Extent: E+W+S+N.I.

For repeated dose toxicity and reproductive toxicity the dose-response relationship shall be assessed for each active substance or substance of concern and, where possible, a NOAEL identified. If it is not possible to identify a NOAEL, the lowest-observed-adverse-effect level (LOAEL) shall be identified. Where appropriate, other dose-effect descriptors may be used as reference values.

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Source: https://www.legislation.gov.uk/eur/2012/528/annex/VI/division/3/division/2/division/1/division/27 (the official version)
Page: https://openlegislation.uk/eu-regulation-2012-528/annex-VI/division-3/division-2/division-1/division-27
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.