# Commission Regulation (EU) No 283/2013 of 1 March 2013 setting out the data requirements for active substances, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market (Text with EEA relevance), Division: Circumstances in which required

Extent: E+W+S+N.I.

The acute inhalation toxicity of the active substance shall be reported where any of the following apply:
the active substance has a vapour pressure > 1 × 10–2 Pa at 20 °C;
the active substance is a powder containing a significant proportion of particles of a diameter < 50 μm ( > 1 % on weight basis);
the active substance is included in products that are powders or are applied by spraying.
The head/nose only exposure shall be used, unless whole body exposure can be justified.

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Source: https://www.legislation.gov.uk/eur/2013/283/annex/section/5/division/5.2/division/5.2.3/division/1 (the official version)
Page: https://openlegislation.uk/eu-regulation-2013-283/annex/section-5/division-5.2/division-5.2.3/division-1
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.