{
  "url": "https://openlegislation.uk/eu-regulation-2015-649/annex-II",
  "json_url": "https://openlegislation.uk/eu-regulation-2015-649/annex-II.json",
  "legislation": "eur/2015/649",
  "legislation_title": "Commission Regulation (EU) 2015/649 of 24 April 2015 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council and the Annex to Commission Regulation (EU) No 231/2012 as regards the use of L-leucine as a carrier for table-top sweeteners in tablets (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2015-649",
  "path": "annex/II",
  "kind": "annex",
  "number": "II",
  "heading": null,
  "text": "In the Annex to Regulation (EU) No 231/2012, the following new entry is inserted after the entry for E 640:\n‘\nE 641 L-LEUCINE\nSynonyms\n2-Aminoisobutylacetic acid; L-2-Amino-4-methylvaleric acid; alpha-Aminoisocaproic acid; (S)-2-Amino-4-methylpentanoic acid; L-Leu\nDefinition\nEinecs\n200-522-0\nCAS number\n61-90-5\nChemical name\nL-Leucine; L-2-Amino-4-methylpentanoic acid\nChemical formula\nC6H13NO2\nMolecular Weight\n131,17\nAssay\nContent not less than 98,5 % and not more than 101,0 % on the anhydrous basis\nDescription\nWhite or almost white crystalline powder or shiny flakes\nIdentification\nSolubility\nSoluble in water, acetic acid, dilute HCl and alkaline hydroxides and carbonates; slightly soluble in ethanol\nSpecific rotation\n[α]D 20 between + 14,5° and + 16,5°\n(4 % solution (anhydrous basis) in 6N HCl)\nPurity\nLoss on drying\nNot more than 0,5 % (100 °C – 105 °C)\nSulphated Ash\nNot more than 0,1 %\nChlorides\nNot more than 200 mg/kg\nSulphates\nNot more than 300 mg/kg\nAmmonium\nNot more than 200 mg/kg\nIron\nNot more than 10 mg/kg\nArsenic\nNot more than 3 mg/kg\nLead\nNot more than 5 mg/kg\nMercury\nNot more than 1 mg/kg\n’",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2015/649/annex/II",
    "retrieved_at": "2026-11-01T14:46:43.633726+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}