# Commission Regulation (EU) 2015/649 of 24 April 2015 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council and the Annex to Commission Regulation (EU) No 231/2012 as regards the use of L-leucine as a carrier for table-top sweeteners in tablets (Text with EEA relevance), Annex II

Extent: E+W+S+N.I.

In the Annex to Regulation (EU) No 231/2012, the following new entry is inserted after the entry for E 640:
‘
E 641 L-LEUCINE
Synonyms
2-Aminoisobutylacetic acid; L-2-Amino-4-methylvaleric acid; alpha-Aminoisocaproic acid; (S)-2-Amino-4-methylpentanoic acid; L-Leu
Definition
Einecs
200-522-0
CAS number
61-90-5
Chemical name
L-Leucine; L-2-Amino-4-methylpentanoic acid
Chemical formula
C6H13NO2
Molecular Weight
131,17
Assay
Content not less than 98,5 % and not more than 101,0 % on the anhydrous basis
Description
White or almost white crystalline powder or shiny flakes
Identification
Solubility
Soluble in water, acetic acid, dilute HCl and alkaline hydroxides and carbonates; slightly soluble in ethanol
Specific rotation
[α]D 20 between + 14,5° and + 16,5°
(4 % solution (anhydrous basis) in 6N HCl)
Purity
Loss on drying
Not more than 0,5 % (100 °C – 105 °C)
Sulphated Ash
Not more than 0,1 %
Chlorides
Not more than 200 mg/kg
Sulphates
Not more than 300 mg/kg
Ammonium
Not more than 200 mg/kg
Iron
Not more than 10 mg/kg
Arsenic
Not more than 3 mg/kg
Lead
Not more than 5 mg/kg
Mercury
Not more than 1 mg/kg
’

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Source: https://www.legislation.gov.uk/eur/2015/649/annex/II (the official version)
Page: https://openlegislation.uk/eu-regulation-2015-649/annex-II
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.