# Commission Regulation (EU) 2017/644 of 5 April 2017 laying down methods of sampling and analysis for the control of levels of dioxins, dioxin-like PCBs and non-dioxin-like PCBs in certain foodstuffs and repealing Regulation (EU) No 589/2014 (Text with EEA relevance), Division 5.5: Limit of quantification

Extent: E+W+S+N.I.

For a bioanalytical screening method, establishment of the LOQ is not an indispensable requirement but the method shall prove that it can differentiate between the blank and the cut-off value. When providing a BEQ-level, a reporting level shall be established to deal with samples showing a response below this level. The reporting level shall be demonstrated to be different from procedure blank samples at least by a factor of three, with a response below the working range. It shall therefore be calculated from samples containing the target compounds around the required minimum level, and not from a S/N ratio or an assay blank.
Limit of quantification (LOQ) for a confirmatory method shall be about one fifth of the maximum level.

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Source: https://www.legislation.gov.uk/eur/2017/644/annex/III/division/5/division/5.5 (the official version)
Page: https://openlegislation.uk/eu-regulation-2017-644/annex-III/division-5/division-5.5
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.