OpenLegislation

Division II.6.3.3.1.2

United Kingdom

Original text. Later amendments are not shown.

Data from repeat dose oral toxicity testing studies shall:

  1. (a)

    allow the evaluation of the functional and morphological changes due to repeated administration of the test substance(s) and how these changes are related to dose;

  2. (b)

    allow the establishment of a NO(A)EL or LO(A)EL or BMDL;

  3. (c)

    inform the choice of dose levels for chronic studies as well as the choice of the most appropriate species for chronic studies.