# Commission Regulation (EU) 2018/782 of 29 May 2018 establishing the methodological principles for the risk assessment and risk management recommendations referred to in Regulation (EC) No 470/2009 (Text with EEA relevance), Division II.6.6.2.1.2

Extent: E+W+S+N.I.

The ADI approach is not appropriate for use in the assessment of essential elements as effects may occur at very low exposure levels, which represent a deficiency in supply. For most minerals and trace elements recommended dietary intake levels have been established by relevant scientific bodies (e.g. EU/EFSA; WHO). Daily dietary exposure estimates for essential elements may be compared with appropriate reference values, such as the recommended daily intake (‘RDI’), dietary reference values (‘DRVs’, previously: recommended daily allowances (‘RDA’)), tolerable daily intakes (‘TDIs’) or tolerable weekly intakes (‘TWIs’) and provisional tolerable weekly intakes (‘PTWI’). These values may be used in the risk assessment, in a way analogous to the ADI. The combined exposure resulting from treatment related residues and exposure from dietary and natural sources shall not exceed the respective reference values.

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Source: https://www.legislation.gov.uk/eur/2018/782/annex/I/division/II/division/II.6/division/II.6.6/division/II.6.6.2/division/II.6.6.2.1/division/II.6.6.2.1.2 (the official version)
Page: https://openlegislation.uk/eu-regulation-2018-782/annex-I/division-II/division-II.6/division-II.6.6/division-II.6.6.2/division-II.6.6.2.1/division-II.6.6.2.1.2
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.